Last data update: 2014.03.03
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SigCheck
Package: SigCheck
Type: Package
Title: Check a gene signature's prognostic performance against random
signatures, known signatures, and permuted data/metadata
Version: 2.4.0
Author: Rory Stark <rory.stark@cruk.cam.ac.uk> and
Justin Norden
Maintainer: Rory Stark <rory.stark@cruk.cam.ac.uk>
Description: While gene signatures are frequently used to predict phenotypes
(e.g. predict prognosis of cancer patients), it it not always
clear how optimal or meaningful they are (cf David Venet,
Jacques E. Dumont, and Vincent Detours' paper "Most Random Gene
Expression Signatures Are Significantly Associated with Breast
Cancer Outcome"). Based on suggestions in that paper,
SigCheck accepts a data set (as an ExpressionSet) and a gene
signature, and compares its performance on survival and/or
classification tasks against
a) random gene signatures of the same length;
b) known, related and unrelated gene signatures;
and c) permuted data and/or metadata.
License: Artistic-2.0
LazyLoad: yes
Depends: R (>= 3.2.0), MLInterfaces, Biobase, e1071, BiocParallel,
survival
Imports: graphics, stats, utils, methods
Suggests: BiocStyle, breastCancerNKI, qusage
biocViews: GeneExpression, Classification, GeneSetEnrichment
NeedsCompilation: no
Packaged: 2016-05-04 05:51:45 UTC; biocbuild
Install log
* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'SigCheck' ...
** R
** data
** inst
** preparing package for lazy loading
Creating a new generic function for 'signature' in package 'SigCheck'
** help
*** installing help indices
converting help for package 'SigCheck'
finding HTML links ... done
SigCheck-package html
finding level-2 HTML links ... done
SigCheckObject-class html
classifyResults html
knownSignatures html
nkiResults html
sigCheck html
sigCheckAll html
sigCheckKnown html
sigCheckPermuted html
sigCheckPlot html
sigCheckRandom html
** building package indices
** installing vignettes
** testing if installed package can be loaded
* DONE (SigCheck)
Making 'packages.html' ... done
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