R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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> library(MEAL)
Loading required package: Biobase
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: MultiDataSet
Setting options('download.file.method.GEOquery'='auto')
Setting options('GEOquery.inmemory.gpl'=FALSE)
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/MEAL/plotVolcano-methods.Rd_%03d_medium.png", width=480, height=480)
> ### Name: plotVolcano
> ### Title: Make a Volcano plot with the probe results
> ### Aliases: plotVolcano
>
> ### ** Examples
>
> if (require(minfiData)){
+ betas <- getBeta(MsetEx)[floor(seq(1, nrow(MsetEx), 10000)), ]
+ set <- prepareMethylationSet(betas, pheno = pData(MsetEx))
+ methyOneVar <- DAPipeline(set, variable_names = "sex", probe_method = "ls")
+ plotEWAS(methyOneVar)
+ }
Loading required package: minfiData
Loading required package: minfi
Loading required package: lattice
Loading required package: GenomicRanges
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: 'S4Vectors'
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: SummarizedExperiment
Loading required package: Biostrings
Loading required package: XVector
Loading required package: bumphunter
Loading required package: foreach
Loading required package: iterators
Loading required package: locfit
locfit 1.5-9.1 2013-03-22
Loading required package: IlluminaHumanMethylation450kmanifest
Loading required package: IlluminaHumanMethylation450kanno.ilmn12.hg19
Your contrast returned 1 individually significant probes; a small but real effect. Consider manually setting the value of pcutoff to return more DMRs, but be warned that doing this increases the risk of Type I errors.
Fitting chr1...
Fitting chr10...
Fitting chr11...
Fitting chr12...
Fitting chr13...
>
>
>
>
>
> dev.off()
null device
1
>