Exact numerical calculation
● Data Source:
CranContrib
● Keywords:
● Alias: LRmoments
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Calculates the probability distribution for a pair of individuals conditionally on 0,1, and 2 IBD alleles.
● Data Source:
CranContrib
● Keywords:
● Alias: q012
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Likelihood for mixtures that may have related contributors and drop-in and drop-out of alleles. For a general description of the problem, see see paraMix . As opposed to paraMix , drop-in and drop-out of alleles are allowed. The likelihood is based on simulations from an urn model. Possible mixtures are simulated by applying drop-in and drop-out to genotypes for the assumed contributors. Genotypes for unknown contributors are simulated conditioned on the pedigree.
● Data Source:
CranContrib
● Keywords:
● Alias: simLR
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Distribution of LR(HP) and LR(HD) are calculated as well as some summary statistics.
● Data Source:
CranContrib
● Keywords:
● Alias: LRstat
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Calculates E(LR(HP)), SD(LR(HP) and SD(LR(HD)) exactly Answers is independent of allele frequencies except for SD(LR(HD))
● Data Source:
CranContrib
● Keywords:
● Alias: tableELRHP
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Based on conditional distribution given IBD from q012 , the joint probability distribution for two individuals are given for specified IBD probabilities
● Data Source:
CranContrib
● Keywords: ~kwd1, ~kwd2
● Alias: qkappa
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Likelihood for mixtures with related contributors based on Familias . For a general description of the problem, see paraMix . As opposed to paraMix this function uses the R version of Familias for likelihood calculation and therefore theta-correction, mutation models and silent allele frequencies (but not X-chromosomes or simulation) are accomodated.
● Data Source:
CranContrib
● Keywords:
● Alias: famMix
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Mixtures are simulated and LR (likelihood ratio) calculations are performed. Complex pedigrees, possibly with inbreeding, theta correction, mutation and silent alleles, are allowed. General conditioning is also accounted in the simulation. There is also a function pvalue.machine that calculates tail probabilities for LR-s.
● Data Source:
CranContrib
● Keywords: package
● Alias: euroMix, euroMix-package
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Genotype data are transformed from lines two columns. If there is only one column for each marker and two lines for each individual, the data is transformed so that there is one line for each individual. The pecularities of the input format of Familias is handled.
● Data Source:
CranContrib
● Keywords:
● Alias: convertToFamilias
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A linkdat object is created. MERLIN files can be generated or mixtures can be generated based on existing files. This function requires MERLIN to be installed and correctly pointed to in the PATH environment variable.
● Data Source:
CranContrib
● Keywords:
● Alias: simMixMerlin
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