Maximization step in the EM algorithm for parameterized bivariate 2-component Gaussian mixture models with $(1-p)N(0, 0, 1, 1, 0) + pN(mu, mu, sigma^2, sigma^2, rho)$.
Expectation step in the EM algorithm for parameterized bivariate 2-component Gaussian mixture models with (1-p)N(0, 0, 1, 1, 0) + pN(mu, mu, sigma, sigma, rho).
This package estimates the reproducibility of observations on a pair of replicate rank lists. It consists of three components: (1) plotting the correspondence curve to visualize reproducibility, (2) quantifying reproducibility using a copula mixture model and estimating the posterior probability for each obsrvation to be irreproducible (local irreproducible discovery rate), and (3) ranking and selecting observations by their irreproducibility.
providing 
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