Deregulation p-values based on deregulation scores. They are calculated as fraction of permutations that give more extreme deregulation scores than for original data.
Returns probabilities of differential expression for genes under perturbation of a set of regulators. Takes as input perturbation data and beliefs about known genes.
Regulation scores reflect the actual regulatory influence of the regulators on the genes. For each regulator, these are probabilities of differential expression averaged over all perturbation experiments that affect the regulator.
providing 
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