diggle.linear.power
(Package: longpower) :
Sample size calculations for difference in slopes between two groups.
This function performs the sample size calculation for difference in slopes between two groups. See Diggle et al (2002) for parameter definitions and other details.
The longpower package contains functions for computing power and sample size for linear models of longitudinal data based on the formula due to Liu and Liang (1997) and Diggle et al (1994). Either formula is expressed in terms of marginal model or Generalized Estimating Equations (GEE) parameters. This package contains functions which translate pilot mixed effect model parameters (e.g. random intercept and/or slope) into marginal model parameters so that the formulas of Diggle et al or Liu and Liang formula can be applied to produce sample size calculations for two sample longitudinal designs assuming known variance. The package also handles the categorical time Mixed Model of Repeated Measures (MMRM) using the formula of Lu, Luo, and Chen (2008)
lmmpower
(Package: longpower) :
Sample size calculations for linear mixed models of rate of change based on
These functions compute sample size for linear mixed models based on the formula due to Diggle (2002) or Liu and Liang (1997). These formulae are expressed in terms of marginal model or Generalized Estimating Equations (GEE) parameters. These functions translate pilot mixed effect model parameters (e.g. random intercept and/or slope, fixed effects, etc.) into marginal model parameters so that either formula can be applied to equivalent affect. Pilot estimates are assumed to be from an appropriate "placebo" group and the parameter of interest is assumed to be the rate of change over time of the outcome.
power.mmrm
(Package: longpower) :
Linear mixed model sample size calculations.
This function performs the sample size calculation for a mixed model of repeated measures with general correlation structure. See Lu, Luo, & Chen (2008) for parameter definitions and other details. This function executes Formula (3) on page 4.
This function performs the sample size calculation for a mixed model of repeated measures with AR(1) correlation structure. See Lu, Luo, & Chen (2008) for parameter definitions and other details.
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