preprocess
(Package: triform) :
Preprocess BED-files with reads to calculate chromosome coverage
Given a directory with BED-files describing ChIP-seq reads, makes coverage files (1 pr chromosome) describing tag counts along the chromosomes. Reads in all available BED-files in the given directory is first converted to IRanges objects and saved as RData files. The preprocessing ends by creating one file for each chromosome, with the calculated coverage on the different strands for different BED-files.
The Triform method uses model-free statistics to identify peak-like distributions of sequencing reads, taking advantage of an improved peak definition in combination with known profile characteristics.
providing 
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