trioSim
(Package: trioGxE) :
Simulate informative case-parent trios
trioSim() simulates parental genotypes, child genotypes, environmental attribute and sub-population membership on affected trios with informative mating types from a stratified population. All genotypes are at a test locus that is linked to a causal locus.
● Data Source:
CranContrib
● Keywords: datagen
● Alias: trioSim
●
0 images
|
trioGxE estimates statistical interaction (GxE) between a single nucleotide polymorphism (SNP) and a continuous environmental or non-genetic attributes in case-parent trio data by fitting a generalized additive model (GAM) using a penalized iteratively re-weighted least squares algorithm.
● Data Source:
CranContrib
● Keywords: methods
● Alias: trioGxE
●
0 images
|
|
Internal pirls.trio functions
● Data Source:
CranContrib
● Keywords: internal
● Alias: pre.pirls
●
0 images
|
|
Performs permutation test of gene-environment interaction based on the associated penalized maximum likelihood estimates obtained by fitting a generalized additive model to case-parent trio data.
● Data Source:
CranContrib
● Keywords: methods
● Alias: test.trioGxE
●
0 images
|
The function plot.trioGxE uses the calculations made in trioGxE and plots the point- and interval-estimates of gene-environment interaction between a single nucleotide polymorphism (SNP) and a continuously varying environmental or non-genetic covariate in case-parent trio data.
● Data Source:
CranContrib
● Keywords: methods
● Alias: plot.trioGxE
●
0 images
|
hypoTrioDat
(Package: trioGxE) :
Simulated data for a hypothetical example
A simulated data set with 1000 informative case-parent trios to illustrate the trioGxE package.
● Data Source:
CranContrib
● Keywords: dataset
● Alias: hypoTrioDat
●
0 images
|
providing 
.