Last data update: 2014.03.03
|
Haplin
Package: Haplin
Title: Analyzing Case-Parent Triad and/or Case-Control Data with SNP
Haplotypes
Version: 6.0.1
Date: 2016-05-25
Type: Package
Author: Hakon K. Gjessing
Maintainer: Hakon K. Gjessing <hakon.gjessing@fhi.no>
Depends: GenABEL, DatABEL
Imports: utils, stats, graphics, grDevices, parallel, tools, mgcv,
MASS, SuppDists, snow
Description: Performs genetic association analyses of case-parent triad (trio) data with multiple markers. It can also incorporate complete or incomplete control triads, for instance independent control children. Estimation is based on haplotypes, for instance SNP haplotypes, even though phase is not known from the genetic data. Haplin estimates relative risk (RR + conf.int.) and p-value associated with each haplotype. It uses maximum likelihood estimation to make optimal use of data from triads with missing genotypic data, for instance if some SNPs has not been typed for some individuals. Haplin also allows estimation of effects of maternal haplotypes and parent-of-origin effects, particularly appropriate in perinatal epidemiology. Haplin allows special models, like X-inactivation, to be fitted on the X-chromosome. A GxE analysis allows testing interactions between environment and all estimated genetic effects.
License: GPL (>= 2)
URL: http://folk.uib.no/gjessing/genetics/software/haplin/
NeedsCompilation: no
Packaged: 2016-05-25 17:09:49 UTC; hkgjess
Repository: CRAN
Date/Publication: 2016-05-26 17:44:32
Install log
* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'Haplin' ...
** package 'Haplin' successfully unpacked and MD5 sums checked
** R
** inst
** preparing package for lazy loading
** help
*** installing help indices
converting help for package 'Haplin'
finding HTML links ... done
cbindFiles html
convertPed html
gwaaToHaplin html
gxe html
hapPower html
hapRun html
hapSim html
haplin html
haplinSlide html
haplinStrat html
haplinTDT html
haptable html
lineByLine html
output html
pQQ html
pedToHaplin html
plot.haplin html
plot.haplinTDT html
plot.haptable html
prepPed html
print.haplin html
print.summary.haplin html
rbindFiles html
Rd warning: /tmp/RtmpuQQNai/R.INSTALL2ac72212602f/Haplin/man/rbindFiles.Rd:26: missing file link 'rbind'
snpPos html
snpPower html
snpSampleSize html
suest html
summary.haplin html
summary.haplinTDT html
toDataFrame html
** building package indices
** testing if installed package can be loaded
* DONE (Haplin)
Making 'packages.html' ... done
|