Last data update: 2014.03.03
|
SomatiCA
Package: SomatiCA
Type: Package
Title: SomatiCA: identifying, characterizing, and quantifying somatic
copy number aberrations from cancer genome sequencing
Version: 2.2.0
Date: 2016-04-15
Author: Mengjie Chen <mengjie.chen@yale.edu>, Hongyu Zhao
<hongyu.zhao@yale.edu>
Maintainer: Mengjie Chen <mengjie.chen@yale.edu>
Imports: foreach, lars, sn, DNAcopy, methods, rebmix, GenomicRanges,
IRanges
Depends: R (>= 2.14.0), lars, DNAcopy, foreach, methods, rebmix,
GenomicRanges, IRanges, doParallel
Enhances: sn, SomatiCAData
Description: SomatiCA is a software suite that is capable of
identifying, characterizing, and quantifying somatic CNAs from
cancer genome sequencing. First, it uses read depths and lesser
allele frequencies (LAF) from mapped short sequence reads to
segment the genome and identify candidate CNAs. Second,
SomatiCA estimates the admixture rate from the relative
copy-number profile of tumor-normal pair by a Bayesian finite
mixture model. Third, SomatiCA quantifies absolute somatic
copy-number and subclonality for each genomic segment to guide
its characterization. Results from SomatiCA can be further
integrated with single nucleotide variations (SNVs) to get a
better understanding of the tumor evolution.
License: GPL (>=2)
biocViews: Sequencing, CopyNumberVariation
PackageStatus: Deprecated
NeedsCompilation: no
Packaged: 2016-05-04 04:51:18 UTC; biocbuild
Install log
* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'SomatiCA' ...
** R
** data
** inst
** preparing package for lazy loading
Warning: replacing previous import 'sn::coef' by 'rebmix::coef' when loading 'SomatiCA'
Warning: replacing previous import 'rebmix::split' by 'GenomicRanges::split' when loading 'SomatiCA'
Warning: replacing previous import 'sn::sd' by 'IRanges::sd' when loading 'SomatiCA'
** help
*** installing help indices
converting help for package 'SomatiCA'
finding HTML links ... done
GCbiasRemoval html
GCcontent html
GCcount html
MergeSegment html
SomatiCA-package html
SomatiCAFormat-methods html
SomatiCAUsersGuide html
SomatiCApipe html
admixtureRate html
collapse html
copynumberCorrected html
denoise html
larsCBSsegment html
plotSegment html
plotSubclonality html
refineSegment html
segmentGCbiasRemoval html
segwithratio html
somaticRatio html
subclonality html
** building package indices
** installing vignettes
** testing if installed package can be loaded
Warning: replacing previous import 'sn::coef' by 'rebmix::coef' when loading 'SomatiCA'
Warning: replacing previous import 'rebmix::split' by 'GenomicRanges::split' when loading 'SomatiCA'
Warning: replacing previous import 'sn::sd' by 'IRanges::sd' when loading 'SomatiCA'
Warning: Package 'SomatiCA' is deprecated and will be removed from Bioconductor
version 3.3
* DONE (SomatiCA)
Making 'packages.html' ... done
|