tRanslatome

Package: tRanslatome
Type: Package
Title: Comparison between multiple levels of gene expression
Version: 1.10.0
Date: 2015-08-20
Author: Toma Tebaldi, Erik Dassi, Galena Kostoska
Maintainer: Toma Tebaldi <tebaldi@science.unitn.it>, Erik Dassi <erik.dassi@unitn.it>
Depends: R (>= 2.15.0), methods, limma, sigPathway, samr, anota, DESeq,
edgeR, RankProd, topGO, org.Hs.eg.db, GOSemSim, Heatplus,
gplots, plotrix, Biobase
Description: Detection of differentially expressed genes (DEGs) from the comparison of two biological conditions (treated vs. untreated, diseased vs. normal, mutant vs. wild-type) among different levels of gene expression (transcriptome ,translatome, proteome), using several statistical methods: Rank Product, Translational Efficiency, t-test, SAM, Limma, ANOTA, DESeq, edgeR. Possibility to plot the results with scatterplots, histograms, MA plots, standard deviation (SD) plots, coefficient of variation (CV) plots. Detection of significantly enriched post-transcriptional regulatory factors (RBPs, miRNAs, etc) and Gene Ontology terms in the lists of DEGs previously identified for the two expression levels. Comparison of GO terms enriched only in one of the levels or in both. Calculation of the semantic similarity score between the lists of enriched GO terms coming from the two expression levels. Visual examination and comparison of the enriched terms with heatmaps, radar plots and barplots.
License: GPL-3
LazyLoad: yes
biocViews: CellBiology, GeneRegulation, Regulation, GeneExpression,
DifferentialExpression, Microarray, HighThroughputSequencing,
QualityControl, GO, MultipleComparisons, Bioinformatics
Packaged: 2016-05-04 04:58:42 UTC; biocbuild
NeedsCompilation: no

Install log

* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'tRanslatome' ...
** R
** data
** inst
** preparing package for lazy loading

groupGOTerms: 	GOBPTerm, GOMFTerm, GOCCTerm environments built.
** help
*** installing help indices
  converting help for package 'tRanslatome'
    finding HTML links ... done
    CVplot                                  html  
    DEGs                                    html  
    DEGs.table                              html  
    EnrichedSets                            html  
    FC.threshold                            html  
    GOComparison                            html  
    GOEnrichment                            html  
    GOsets                                  html  
    GOsims                                  html  
    Heatmap                                 html  
    Histogram                               html  
    IdentityPlot                            html  
    MAplot                                  html  
    Radar                                   html  
    RegulatoryEnrichment                    html  
    SDplot                                  html  
    Scatterplot                             html  
    SimilarityPlot                          html  
    TranslatomeDataset                      html  
    average.similarity.scores               html  
    computeDEGs                             html  
    enriched.table                          html  
    getConditionA                           html  
    getConditionB                           html  
    getConditionC                           html  
    getConditionD                           html  
    getConditionLabels                      html  
    getDEGs                                 html  
    getDEGsMethod                           html  
    getDataType                             html  
    getExprMatrix                           html  
    getLevelLabels                          html  
    identity.matrix                         html  
    label.condition                         html  
    label.level.DEGs                        html  
    label.level.enriched                    html  
    newTranslatomeDataset                   html  
    significance.threshold                  html  
    similarity.matrix                       html  
    tRanslatome-package                     html  
    tRanslatomeSampleData                   html  
** building package indices
** installing vignettes
** testing if installed package can be loaded

groupGOTerms: 	GOBPTerm, GOMFTerm, GOCCTerm environments built.
* DONE (tRanslatome)
Making 'packages.html' ... done