Package: CODEX
Type: Package
Title: A Normalization and Copy Number Variation Detection Method for
Whole Exome Sequencing
Version: 1.4.0
Author: Yuchao Jiang, Nancy R. Zhang
Maintainer: Yuchao Jiang <yuchaoj@wharton.upenn.edu>
Description: A normalization and copy number variation calling procedure for
whole exome DNA sequencing data. CODEX relies on the availability of
multiple samples processed using the same sequencing pipeline for
normalization, and does not require matched controls. The normalization
model in CODEX includes terms that specifically remove biases due to GC
content, exon length and targeting and amplification efficiency, and latent
systemic artifacts. CODEX also includes a Poisson likelihood-based recursive
segmentation procedure that explicitly models the count-based exome
sequencing data.
License: GPL-2
Depends: R (>= 3.2.3), Rsamtools, GenomeInfoDb, BSgenome.Hsapiens.UCSC.hg19, IRanges, Biostrings
Suggests: WES.1KG.WUGSC
biocViews: ExomeSeq, Normalization, QualityControl, CopyNumberVariation
LazyData: yes
NeedsCompilation: no
Packaged: 2016-05-04 06:01:34 UTC; biocbuild
Package: BSgenome.Hsapiens.UCSC.hg19.masked
Title: Full masked genome sequences for Homo sapiens (UCSC version
hg19)
Description: Full genome sequences for Homo sapiens (Human) as provided by UCSC (hg19, Feb. 2009) and stored in Biostrings objects. The sequences are the same as in BSgenome.Hsapiens.UCSC.hg19, except that each of them has the 4 following masks on top: (1) the mask of assembly gaps (AGAPS mask), (2) the mask of intra-contig ambiguities (AMB mask), (3) the mask of repeats from RepeatMasker (RM mask), and (4) the mask of repeats from Tandem Repeats Finder (TRF mask). Only the AGAPS and AMB masks are "active" by default.
Version: 1.3.99
Author: The Bioconductor Dev Team
Maintainer: Bioconductor Package Maintainer
<maintainer@bioconductor.org>
Depends: BSgenome (>= 1.31.8), BSgenome.Hsapiens.UCSC.hg19
Imports: BSgenome, BSgenome.Hsapiens.UCSC.hg19
License: Artistic-2.0
organism: Homo sapiens
species: Human
provider: UCSC
provider_version: hg19
release_date: Feb. 2009
release_name: Genome Reference Consortium GRCh37
source_url: http://hgdownload.cse.ucsc.edu/goldenPath/hg19/bigZips/
biocViews: AnnotationData, Genetics, BSgenome, Homo_sapiens
Packaged: 2014-01-08 20:13:51 UTC; hpages