R: descriptive plot of expression against genotype for cisAssoc...
eqBox
R Documentation
descriptive plot of expression against genotype for cisAssoc
results
Description
descriptive plot of expression against genotype for cisAssoc
results
Usage
eqBox(gene, snp, se, tf, radius=1e6, genome="hg19", ...)
eqDesc(gene, snp, se, tf, radius=1e6, genome="hg19", ...)
Arguments
gene
identifier of gene in SummarizedExperiment se, must be present
in rownames(se)
snp
identifier of variant in VCF referenced by tf
se
SummarizedExperiment instance
tf
TabixFile reference for a VCF file that has been bgzipped
and tabix-indexed
radius
in order to limit the VCF import, we filter variants to those within a radius
around the selected gene – it is assumed that the selected snp will
exist in that region (we can't extract SNP by name from vcf...)
genome
a simple genome identifier tag
...
(not used with eqDesc)
will embellish plot; xlab and ylab already taken care of
Details
The chromosome names in the VCF and the seqlevelsStyle of the Summarized
Experiment must match.
Value
eqBox produces a boxplot for all categories (including NA) of genotype.
eqDesc tabulates the genotype calls in categories.
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)
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> library(GGtools)
Loading required package: GGBase
Loading required package: snpStats
Loading required package: survival
Loading required package: Matrix
Loading required package: data.table
Loading required package: parallel
Loading required package: Homo.sapiens
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: BiocGenerics
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: IRanges
Loading required package: S4Vectors
Attaching package: 'S4Vectors'
The following objects are masked from 'package:Matrix':
colMeans, colSums, expand, rowMeans, rowSums
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
Attaching package: 'IRanges'
The following object is masked from 'package:data.table':
shift
Loading required package: OrganismDbi
Loading required package: GenomicFeatures
Loading required package: GenomeInfoDb
Loading required package: GenomicRanges
Loading required package: GO.db
Loading required package: org.Hs.eg.db
Loading required package: TxDb.Hsapiens.UCSC.hg19.knownGene
Attaching package: 'GGtools'
The following object is masked from 'package:stats':
getCall
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/GGtools/eqBox.Rd_%03d_medium.png", width=480, height=480)
> ### Name: eqBox
> ### Title: descriptive plot of expression against genotype for cisAssoc
> ### results
> ### Aliases: eqBox eqDesc
> ### Keywords: models
>
> ### ** Examples
>
> if (require(VariantAnnotation)) {
+ data(lgeu)
+ lgeue = lgeu[,which(lgeu$popcode=="CEU")]
+ tf20 = TabixFile(system.file("vcf/c20exch.vcf.gz", package="GGtools"))
+ eqBox( "ENSG00000126005.10", "rs2425038", lgeue, tf20 )
+ }
Loading required package: VariantAnnotation
Loading required package: SummarizedExperiment
Loading required package: Rsamtools
Loading required package: Biostrings
Loading required package: XVector
Attaching package: 'VariantAnnotation'
The following object is masked from 'package:base':
tabulate
Warning message:
In .local(x, ...) : non-diploid variants are set to NA
>
>
>
>
>
> dev.off()
null device
1
>