Calculates conditional p-values proposed in Kulinskaya (2008) to overcome the problems of asymetric distributions, the Haldane 2-sided test as implemented by Wiggington et al (2005) and the 1-sided test for inbreeding.
Usage
HWE2sided(geno, qplot = F, title = NULL)
Arguments
geno
Vector of genotype counts: no. heterozygotes followed by the nos. homozygotes
qplot
If qplot is true the distribution of the null hypothesis is plotted
title
Title for the plot
Value
pval.cond
Conditional p-value
pval.H
2-sided Haldane p-value
pval.inbreed
1-sided test for inbreeding
Author(s)
Alex Lewin
References
Kulinskaya and Lewin 2008
See Also
HWE2sided.table
Examples
geno <- c(20,73,7)
HWE2sided(geno)
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(LDtests)
> png(filename="/home/ddbj/snapshot/RGM3/R_CC/result/LDtests/HWE2sided.Rd_%03d_medium.png", width=480, height=480)
> ### Name: HWE2sided
> ### Title: P-values for three different tests of HWE
> ### Aliases: HWE2sided
> ### Keywords: htest
>
> ### ** Examples
>
> geno <- c(20,73,7)
> HWE2sided(geno)
$pval.cond
[1] 0.01248399
$pval.H
[1] 0.007101873
$pval.inbreed
[1] 0.007101873
>
>
>
>
>
> dev.off()
null device
1
>