Last data update: 2014.03.03

R: Spatial trend of microarray spots statistic
arrayTrendR Documentation

Spatial trend of microarray spots statistic

Description

The function arrayTrend computes the spatial trend.

Usage

## Default S3 method:
arrayTrend(Statistic, Col, Row, ...)
## S3 method for class 'arrayCGH'
arrayTrend(arrayCGH, variable, ...)

Arguments

Statistic

Statistic to be smoothed.

Col

Vector of columns coordinates.

Row

Vector of rows coordinates.

arrayCGH

Object of class arrayCGH.

variable

Variable to be smooth.

...

Parameters to be passed to loess function.

Details

Spatial trend of microarray spots statistic.

Value

Either a data frame with elements :

Trend

Trend fitted by loess function.

Col

Vector of columns coordinates.

Row

Vector of rows coordinates.

or the element Trend is added to the data.frame arrayValues of the arrayCGH object.

Note

People interested in tools for array-CGH analysis can visit our web-page: http://bioinfo.curie.fr.

Author(s)

Philippe Hupé, Philippe.Hupe@curie.fr.

References

P. Neuvial, P. Hupé, I. Brito, S. Liva, E. Manié, C. Brennetot, A. Aurias, F. Radvanyi, and E. Barillot. Spatial normalization of array-CGH data. BMC Bioinformatics, 7(1):264. May 2006.

See Also

loess, loess.control.

Examples

data(spatial)  ## arrays with local spatial effects

edgeTrend <- arrayTrend(edge, "LogRatio", span=0.03, degree=1,
iterations=3, family="symmetric") 
arrayPlot(edgeTrend, "Trend", main="Spatial trend of array CGH", bar="v") 

Results


R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(MANOR)
Loading required package: GLAD

######################################################################################

Have fun with GLAD

For smoothing it is possible to use either
the AWS algorithm (Polzehl and Spokoiny, 2002,
or the HaarSeg algorithm (Ben-Yaacov and Eldar, Bioinformatics,  2008,

If you use the package with AWS, please cite:
Hupe et al. (Bioinformatics, 2004, and Polzehl and Spokoiny (2002,

If you use the package with HaarSeg, please cite:
Hupe et al. (Bioinformatics, 2004, and (Ben-Yaacov and Eldar, Bioinformatics, 2008,

For fast computation it is recommanded to use
the daglad function with smoothfunc=haarseg

######################################################################################

New options are available in daglad: see help for details.


Attaching package: 'MANOR'

The following object is masked from 'package:base':

    norm

> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/MANOR/arrayTrend.Rd_%03d_medium.png", width=480, height=480)
> ### Name: arrayTrend
> ### Title: Spatial trend of microarray spots statistic
> ### Aliases: arrayTrend arrayTrend.default arrayTrend.arrayCGH
> ### Keywords: smooth loess spatial
> 
> ### ** Examples
> 
> data(spatial)  ## arrays with local spatial effects
> 
> edgeTrend <- arrayTrend(edge, "LogRatio", span=0.03, degree=1,
+ iterations=3, family="symmetric") 
> arrayPlot(edgeTrend, "Trend", main="Spatial trend of array CGH", bar="v") 
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>