Save PMD segments

Description

Save PMD segments in rds format and as tab-delimited file.

Usage

savePMDSegments(PMDs, GRangesFilename, TableFilename)

Arguments

Value

No return value.

Author(s)

Lukas Burger lukas.burger@fmi.ch

Examples

library(MethylSeekR)

# get chromosome lengths
library("BSgenome.Hsapiens.UCSC.hg18")
sLengths=seqlengths(Hsapiens)

# read methylation data
methFname <- system.file("extdata", "Lister2009_imr90_hg18_chr22.tab",
package="MethylSeekR")
meth.gr <- readMethylome(FileName=methFname, seqLengths=sLengths)

#segment PMDs
PMDsegments.gr <- segmentPMDs(m=meth.gr, chr.sel="chr22",
seqLengths=sLengths)

#save PMD segments
savePMDSegments(PMDs=PMDsegments.gr, GRangesFilename="PMDs.gr.rds",
 TableFilename="PMDs.tab")

Results

R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

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Type 'license()' or 'licence()' for distribution details.

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Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
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> library(MethylSeekR)
Loading required package: rtracklayer
Loading required package: GenomicRanges
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
    get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
    rbind, rownames, sapply, setdiff, sort, table, tapply, union,
    unique, unsplit

Loading required package: S4Vectors
Loading required package: stats4

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    colMeans, colSums, expand.grid, rowMeans, rowSums

Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: mhsmm
Loading required package: mvtnorm
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/MethylSeekR/savePMDSegments.Rd_%03d_medium.png", width=480, height=480)
> ### Name: savePMDSegments
> ### Title: Save PMD segments
> ### Aliases: savePMDSegments
> 
> ### ** Examples
> 
> 
> library(MethylSeekR)
> 
> # get chromosome lengths
> library("BSgenome.Hsapiens.UCSC.hg18")
Loading required package: BSgenome
Loading required package: Biostrings
Loading required package: XVector
> sLengths=seqlengths(Hsapiens)
> 
> # read methylation data
> methFname <- system.file("extdata", "Lister2009_imr90_hg18_chr22.tab",
+ package="MethylSeekR")
> meth.gr <- readMethylome(FileName=methFname, seqLengths=sLengths)
reading methylome data
Read 200000 records
> 
> #segment PMDs
> PMDsegments.gr <- segmentPMDs(m=meth.gr, chr.sel="chr22",
+ seqLengths=sLengths)
training PMD-HMM on chromosome chr22
performing viterbi segmentation
creating GRanges object
> 
> #save PMD segments
> savePMDSegments(PMDs=PMDsegments.gr, GRangesFilename="PMDs.gr.rds",
+  TableFilename="PMDs.tab")
> 
> 
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>