A package to perform robust quantitative traits
association testing of copy number variants. It provides
two methods for association study: first, the observed
probe intensity measurement can be directly used to
detect the association of CNV with phenotype of interest.
Second, the most probable copy number is estimated with
the proposed likelihood and the association of the most
probable copy number with phenotype is tested. Also, it
can be used to determine the optimal clustering number
and clustering assignment for each individuals. This
method can be applied to both the independent and
correlated population.
Details
Package:
PedCNV
Type:
Package
Version:
0.1
Date:
2013-09-03
License:
MIT
Main functions:
AssoTestProc
ClusProc
STE
STIM
print.asso
print.clus
plot.clus
Author(s)
Meiling Liu, Sungho Won and Weicheng Zhu
References
On the association analysis of CNV data: fast and
efficient method with family-based samples