Last data update: 2014.03.03

R: Perform a Student's t-test
TtestR Documentation

Perform a Student's t-test

Description

Performs a Student's t-test on the intensity data.

Usage

Ttest(dataset, listofargs)

Arguments

dataset

an R data frame generated with generateDatasetFile

listofargs

a list containing:

- "g" (greater) for significant increase, "l" (lower) for significant decrease, or "two.sided" for both

- either a number indicating the true value of the mean, or a character string indicating the name of the gene to compare with

- a character string specifying the column whose values will be used for the test

- a character string specifying the name of the dataset column to be used to define the replicate, e.g. "GeneName" or "Internal_GeneID"

Value

Returns a list containing:

pValVec

a named vector of p-values

dataset

the dataset with an added column "p.value.mannwhitney"

paste("pValue.ttest", testType, sep="_")

the character string "pValue.ttest" concatenated with the testType (first element of listofargs)

"t test"

the character string "t test"

See Also

MannWhitney, RankProduct

Examples

data(exampleHeader, package="RNAither")
data(exampleDataset, package="RNAither")

pvals1 <- Ttest(dataset, list("l", median(dataset$SigIntensity, na.rm=TRUE), "SigIntensity", "GeneName"))
pValVec1 <- pvals1[[1]]
scoredDataset1 <- pvals1[[2]]

Results


R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

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Type 'contributors()' for more information and
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Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(RNAither)
Loading required package: topGO
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
    get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
    rbind, rownames, sapply, setdiff, sort, table, tapply, union,
    unique, unsplit

Loading required package: graph
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: GO.db
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: IRanges
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    colMeans, colSums, expand.grid, rowMeans, rowSums


Loading required package: SparseM

Attaching package: 'SparseM'

The following object is masked from 'package:base':

    backsolve


groupGOTerms: 	GOBPTerm, GOMFTerm, GOCCTerm environments built.

Attaching package: 'topGO'

The following object is masked from 'package:IRanges':

    members

Loading required package: RankProd
Loading required package: prada
Loading required package: RColorBrewer
Loading required package: grid

Attaching package: 'grid'

The following object is masked from 'package:topGO':

    depth

Loading required package: rrcov
Loading required package: robustbase

Attaching package: 'robustbase'

The following object is masked from 'package:Biobase':

    rowMedians

Scalable Robust Estimators with High Breakdown Point (version 1.3-11)


Attaching package: 'RNAither'

The following object is masked from 'package:IRanges':

    trim

> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/RNAither/Ttest.Rd_%03d_medium.png", width=480, height=480)
> ### Name: Ttest
> ### Title: Perform a Student's t-test
> ### Aliases: Ttest
> ### Keywords: univar
> 
> ### ** Examples
> 
> data(exampleHeader, package="RNAither")
> data(exampleDataset, package="RNAither")
> 
> pvals1 <- Ttest(dataset, list("l", median(dataset$SigIntensity, na.rm=TRUE), "SigIntensity", "GeneName"))
> pValVec1 <- pvals1[[1]]
> scoredDataset1 <- pvals1[[2]]
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>