The relative.height.at.lag parameter should be close to
the relative height of the point, where the curve reaches
its maximal slope. If the fitting fails, try to set this
parameter to a different value.
Value
A list with entries:
mu
numeric scalar:
maximal growth rate parameter
l
numeric
scalar: time lag parameter
z0
numeric
scalar: minimal log(OD) parameter
zmax
numeric scalar: maximal log(OD) parameter
Author(s)
Julien Gagneur
Examples
x <- 1:1000
z <- gompertz(x, mu=0.01, l=200, z0=1, zmax=5)+rnorm(length(x),mean=0,sd=0.25)
guess <- guessCellGrowthParams(x,z,relative.height.at.lag=0.5)
fit <- nls(z~gompertz(x,mu,l,z0,zmax),start=guess)
plot(x,z)
lines(x,predict(fit,x),lwd=2,col="red")
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)
R is free software and comes with ABSOLUTELY NO WARRANTY.
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Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> library(cellGrowth)
Loading required package: locfit
locfit 1.5-9.1 2013-03-22
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/cellGrowth/guessCellGrowthParams.Rd_%03d_medium.png", width=480, height=480)
> ### Name: guessCellGrowthParams
> ### Title: Guess growth models parameters
> ### Aliases: guessCellGrowthParams
>
> ### ** Examples
>
> x <- 1:1000
> z <- gompertz(x, mu=0.01, l=200, z0=1, zmax=5)+rnorm(length(x),mean=0,sd=0.25)
> guess <- guessCellGrowthParams(x,z,relative.height.at.lag=0.5)
> fit <- nls(z~gompertz(x,mu,l,z0,zmax),start=guess)
> plot(x,z)
> lines(x,predict(fit,x),lwd=2,col="red")
>
>
>
>
>
> dev.off()
null device
1
>