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Last data update: 2014.03.03

R: Remove background

bgAdjust

R Documentation

Remove background

Description

Estimate and remove background signal using anti-genomic background probes

Usage

bgAdjust(dat, copy=TRUE)

Arguments

`dat`	a TilingFeatureSet
`copy`	Only relevant when using disk-backed objects. If TRUE a copy will be made leaving the original object (dat) unchanged. The input object will not be preserved if copy=FALSE

Details

Background signal removal using a modified version of the RMA convolution model. The background signal level is estimated within GC-strata using anti-genomic background probes.

Value

a TilingFeatureSet

Author(s)

Martin Aryee <aryee@jhu.edu>

Examples

# See normalizeBetweenSamples