We can calculate how many eQTLs have PPA above the cutoff with the eqtlFinder function.
Usage
eqtlFinder(prob, threshold)
Arguments
prob
matrix or data frame that contains the Posterior
Probability of Association values (output of eqtlMcmc function)
threshold
Threshold to be used to determine which QTLs are significant. This value can be the output of the calculateThreshold function.It must be a numerical value between 0 and 1.
Value
The output of the eqtlFinder is a data frame where the first column contains the names of each gene, the second column contains the names of corresponding markers and the third column contains the PPA value for each significant eQTL.
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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> library(iBMQ)
Loading required package: Biobase
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: ggplot2
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/iBMQ/eqtlFinder.Rd_%03d_medium.png", width=480, height=480)
> ### Name: eqtlFinder
> ### Title: eqtlFinder
> ### Aliases: eqtlFinder
>
> ### ** Examples
>
> data(PPA.liver)
> cutoff.liver <- calculateThreshold(PPA.liver, 0.2)
> eqtl.liver <- eqtlFinder(PPA.liver, cutoff.liver)
>
>
>
>
>
>
> dev.off()
null device
1
>