Last data update: 2014.03.03

R: Discretize and smooth expression values
discreteKernelizeR Documentation

Discretize and smooth expression values

Description

returns discretized kernelized expression values and saves them to a file if argument 'saveToFile' is TRUE. For details on discretization see discretize.

Usage

discreteKernelize(data, chrom, margin = 10, step.width = 1e+05, kernel = rbf,
                  kernelparams = list(gamma = 1/10^13), saveToFile = FALSE)

Arguments

data

MACATData Object

chrom

chromosome to kernelize

margin

symmetric qunatile in percent

step.width

size of the interpolation steps

kernel

kernel function one of rbf, kNN, basePairDistance or your own

kernelparams

list of named kernel parameters

saveToFile

logicval indicating whether to write a flatfile or not; default is FALSE

Details

Filename of the flatfile is: discrete_kernelized_seq_margin_<margin>_chrom_<chrom>.py where <margin> is the discretization parameter and <chrom> the name of the chromosome.

Value

discretized and kernelized expression matrix

Author(s)

The MACAT Development team

See Also

pydata, kernelizeAll

Examples

   #loaddatapkg("stjudem")
   #data(stjude)
   data(stjd)
   discretizedKernelized = discreteKernelize(stjd, 13)

Results


R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(macat)
Loading required package: Biobase
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
    get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
    rbind, rownames, sapply, setdiff, sort, table, tapply, union,
    unique, unsplit

Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: annotate
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: IRanges
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    colMeans, colSums, expand.grid, rowMeans, rowSums

Loading required package: XML
Loading MicroArray Chromosome Analysis Tool...
Loading required packages...

Type 'demo(macatdemo)' for a quick tour...

> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/macat/discreteKernelize.Rd_%03d_medium.png", width=480, height=480)
> ### Name: discreteKernelize
> ### Title: Discretize and smooth expression values
> ### Aliases: discreteKernelize
> ### Keywords: manip
> 
> ### ** Examples
> 
>    #loaddatapkg("stjudem")
>    #data(stjude)
>    data(stjd)
>    discretizedKernelized = discreteKernelize(stjd, 13)
Computing kernel weights
Kernelizing
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>