Method Comparison Regression

Description

Method Comparison Regression. This package provides regression methods to quantify the relation between two measurement methods. In particular it addresses regression problems with errors in both variables and without repeated measurements. The package provides implementations of Deming regression, weighted Deming regression, and Passing-Bablok regression following the CLSI EP09-A3 recommendations for analytical method comparison and bias estimation using patient samples.

Details

The main function for performing regression analysis is mcreg. Various functions for summarizing and plotting regression results are provided (see examples in mcreg).

For user site testing (installation verification) please use the test case suite provided with the package. The test case suite can be run by sourcing the 'runalltests.R' script in the 'unitTests' folder. It requires the XML and Runit packages.

Author(s)

Ekaterina Manuilova <ekaterina.manuilova@roche.com> Andre Schuetzenmeister <andre.schuetzenmeister@roche.com> Fabian Model <fabian.model@roche.com>

References

CLSI EP09-A3 http://www.clsi.org

Results