R Graphical Manual

Last data update: 2014.03.03

R: Simulate meta-analysis outcomes

simulate.metaLik

R Documentation

Simulate meta-analysis outcomes

Simulate one or more meta-analysis outcomes from a fitted metaLik object.

## S3 method for class 'metaLik'
simulate(object, nsim=1, seed=NULL, DL=FALSE, ...)

`object`	an object of class `"metaLik"`.
`nsim`	number of outcome vectors to simulate. Default is `1`.
`seed`	an object specifying if and how the random number generator should be initialized, see `simulate` for details.
`DL`	logical, whether simulation is based on DerSimonian and Laird estimate (DerSimonian and Laird, 1986). Default is `FALSE`, corresponding to simulation from maximum likelihood estimate.
`...`	additional optional arguments.

A dataframe containing the simulated meta-analysis outcomes.

Annamaria Guolo and Cristiano Varin.

DerSimonian, R. and Laird, N. (1986). Meta-Analysis in Clinical Trials. Controlled Clinical Trials 7, 177–188.

data(vaccine)
m <- metaLik(y~latitude, data=vaccine, sigma2=sigma2)
sim <- simulate(m, nsim=2)
sim