This class holds preprocessed data for Illumina methylation
microarrays.
Usage
## Constructor
RatioSet(Beta = NULL, M = NULL, CN = NULL, ...)
## Data extraction / Accessors
## S4 method for signature 'RatioSet'
getBeta(object)
## S4 method for signature 'RatioSet'
getM(object)
## S4 method for signature 'RatioSet'
getCN(object)
## S4 method for signature 'RatioSet'
preprocessMethod(object)
Arguments
object
A RatioSet.
Beta
A matrix of beta values (between zero and one)
with each row being a methylation loci and each column a sample.
M
A matrix of log-ratios (between minus infinity and infinity)
with each row being a methylation loci and each column a sample.
CN
An optional matrix of copy number estimates
with each row being a methylation loci and each column a sample.
...
For the constructor: additional objects passes to the
eSet constructor, particular a phenoData slot. For
getM these values gets passed onto getBeta.
Details
This class inherits from eSet. Essentially the class
is a representation of a Beta matrix and/or a M matrix
and optionally a CN (copy number) matrix linked to a
pData data frame.
In addition, an annotation and a preprocessMethod slot is present. The annotation slot describes
the type of array and also which annotation package to use. The preprocessMethod slot describes
the kind of preprocessing that resulted in this dataset.
For a RatioSet, M-values are defined as logit2 of the
Beta-values if the M-values are not present in the object. Similarly,
if only M-values are present in the object, Beta-values are
ilogit2 of the M-values.
Constructor
Instances are constructed using the RatioSet function with the
arguments outlined above.
eSet for the basic class structure.
Objects of this class are typically created from an
MethylSet using ratioConvert.
Examples
showClass("RatioSet")
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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Platform: x86_64-pc-linux-gnu (64-bit)
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Type 'demo()' for some demos, 'help()' for on-line help, or
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> library(minfi)
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: lattice
Loading required package: GenomicRanges
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: 'S4Vectors'
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: SummarizedExperiment
Loading required package: Biostrings
Loading required package: XVector
Loading required package: bumphunter
Loading required package: foreach
Loading required package: iterators
Loading required package: locfit
locfit 1.5-9.1 2013-03-22
Setting options('download.file.method.GEOquery'='auto')
Setting options('GEOquery.inmemory.gpl'=FALSE)
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/minfi/RatioSet-class.Rd_%03d_medium.png", width=480, height=480)
> ### Name: RatioSet-class
> ### Title: RatioSet instances
> ### Aliases: RatioSet-class RatioSet getBeta,RatioSet-method
> ### getM,RatioSet-method getCN,RatioSet-method
> ### preprocessMethod,RatioSet-method show,RatioSet-method
> ### initialize,RatioSet-method
>
> ### ** Examples
>
> showClass("RatioSet")
Class "RatioSet" [package "minfi"]
Slots:
Name: preprocessMethod assayData phenoData
Class: character AssayData AnnotatedDataFrame
Name: featureData experimentData annotation
Class: AnnotatedDataFrame MIAxE character
Name: protocolData .__classVersion__
Class: AnnotatedDataFrame Versions
Extends:
Class "eSet", directly
Class "VersionedBiobase", by class "eSet", distance 2
Class "Versioned", by class "eSet", distance 3
>
>
>
>
>
> dev.off()
null device
1
>