Last data update: 2014.03.03

R: perTurbo classification
perTurboClassificationR Documentation

perTurbo classification

Description

Classification using the PerTurbo algorithm.

Usage

perTurboClassification(object, assessRes, scores = c("prediction", "all",
  "none"), pRegul, sigma, inv, reg, fcol = "markers")

Arguments

object

An instance of class "MSnSet".

assessRes

An instance of class "GenRegRes", as generated by svmRegularisation.

scores

One of "prediction", "all" or "none" to report the score for the predicted class only, for all cluster or none.

pRegul

If assessRes is missing, a pRegul must be provided. See perTurboOptimisation for details.

sigma

If assessRes is missing, a sigma must be provided. See perTurboOptimisation for details.

inv

The type of algorithm used to invert the matrix. Values are : "Inversion Cholesky" (chol2inv), "Moore Penrose" (ginv), "solve" (solve), "svd" (svd). Default value is "Inversion Cholesky".

reg

The type of regularisation of matrix. Values are "none", "trunc" or "tikhonov". Default value is "tikhonov".

fcol

The feature meta-data containing marker definitions. Default is markers.

Value

An instance of class "MSnSet" with perTurbo and perTurbo.scores feature variables storing the classification results and scores respectively.

Author(s)

Thomas Burger and Samuel Wieczorek

References

N. Courty, T. Burger, J. Laurent. "PerTurbo: a new classification algorithm based on the spectrum perturbations of the Laplace-Beltrami operator", The European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases (ECML-PKDD 2011), D. Gunopulos et al. (Eds.): ECML PKDD 2011, Part I, LNAI 6911, pp. 359 - 374, Athens, Greece, September 2011.

Examples

library(pRolocdata)
data(dunkley2006)
## reducing parameter search space 
params <- perTurboOptimisation(dunkley2006,
                               pRegul = 2^seq(-2,2,2),
                               sigma = 10^seq(-1, 1, 1),
                               inv = "Inversion Cholesky",
                               reg ="tikhonov",
                               times = 3)
params
plot(params)
f1Count(params)
levelPlot(params)
getParams(params)
res <- perTurboClassification(dunkley2006, params)
getPredictions(res, fcol = "perTurbo")
getPredictions(res, fcol = "perTurbo", t = 0.75)
plot2D(res, fcol = "perTurbo")

Results


R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
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> library(pRoloc)
Loading required package: MSnbase
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
    get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
    rbind, rownames, sapply, setdiff, sort, table, tapply, union,
    unique, unsplit

Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: mzR
Loading required package: Rcpp
Loading required package: BiocParallel
Loading required package: ProtGenerics

This is MSnbase version 1.20.7 
  Read '?MSnbase' and references therein for information
  about the package and how to get started.


Attaching package: 'MSnbase'

The following object is masked from 'package:stats':

    smooth

The following object is masked from 'package:base':

    trimws

Loading required package: MLInterfaces
Loading required package: annotate
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: IRanges
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    colMeans, colSums, expand.grid, rowMeans, rowSums

Loading required package: XML
Loading required package: cluster

This is pRoloc version 1.12.4 
  Read '?pRoloc' and references therein for information
  about the package and how to get started.

> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/pRoloc/perTurboClassification.Rd_%03d_medium.png", width=480, height=480)
> ### Name: perTurboClassification
> ### Title: perTurbo classification
> ### Aliases: perTurboClassification
> 
> ### ** Examples
> 
> library(pRolocdata)

This is pRolocdata version 1.10.0.
Use 'pRolocdata()' to list available data sets.
> data(dunkley2006)
> ## reducing parameter search space 
> params <- perTurboOptimisation(dunkley2006,
+                                pRegul = 2^seq(-2,2,2),
+                                sigma = 10^seq(-1, 1, 1),
+                                inv = "Inversion Cholesky",
+                                reg ="tikhonov",
+                                times = 3)
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> params
Object of class "GenRegRes"
Algorithm: perTurbo 
Hyper-parameters:
 pRegul: 0.25 1 4
 sigma: 0.1 1 10
 other: Inversion Cholesky tikhonov
Design:
 Replication: 3 x 5-fold X-validation
 Partitioning: 0.2/0.8 (test/train)
Results
 macro F1:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
 0.6667  0.7222  0.7778  0.8148  0.8889  1.0000 
 best sigma: 0.1 1   
 best pRegul: 4 0.25   
> plot(params)
> f1Count(params)
    0.25  4
0.1   NA  0
1      1 NA
> levelPlot(params)
> getParams(params)
 sigma pRegul 
  1.00   0.25 
> res <- perTurboClassification(dunkley2006, params)
> getPredictions(res, fcol = "perTurbo")
ans
     ER lumen   ER membrane         Golgi Mitochondrion            PM 
           17           184            96           106            75 
      Plastid      Ribosome           TGN       vacuole 
           26            51            26           108 
MSnSet (storageMode: lockedEnvironment)
assayData: 689 features, 16 samples 
  element names: exprs 
protocolData: none
phenoData
  sampleNames: M1F1A M1F4A ... M2F11B (16 total)
  varLabels: membrane.prep fraction replicate
  varMetadata: labelDescription
featureData
  featureNames: AT1G09210 AT1G21750 ... AT4G39080 (689 total)
  fvarLabels: assigned evidence ... perTurbo.pred (11 total)
  fvarMetadata: labelDescription
experimentData: use 'experimentData(object)'
  pubMedIds: 16618929 
Annotation:  
- - - Processing information - - -
Loaded on Thu Jul 16 22:53:08 2015. 
Normalised to sum of intensities. 
Added markers from  'mrk' marker vector. Thu Jul 16 22:53:08 2015 
Performed perTurbo prediction (sigma=1 pRegul=0.25) Thu Jul  7 01:45:34 2016 
Added perTurbo predictions according to global threshold = 0 Thu Jul  7 01:45:34 2016 
 MSnbase version: 1.17.12 
> getPredictions(res, fcol = "perTurbo", t = 0.75)
ans
     ER lumen   ER membrane         Golgi Mitochondrion            PM 
           17           184            96           106            75 
      Plastid      Ribosome           TGN       vacuole 
           26            51            26           108 
MSnSet (storageMode: lockedEnvironment)
assayData: 689 features, 16 samples 
  element names: exprs 
protocolData: none
phenoData
  sampleNames: M1F1A M1F4A ... M2F11B (16 total)
  varLabels: membrane.prep fraction replicate
  varMetadata: labelDescription
featureData
  featureNames: AT1G09210 AT1G21750 ... AT4G39080 (689 total)
  fvarLabels: assigned evidence ... perTurbo.pred (11 total)
  fvarMetadata: labelDescription
experimentData: use 'experimentData(object)'
  pubMedIds: 16618929 
Annotation:  
- - - Processing information - - -
Loaded on Thu Jul 16 22:53:08 2015. 
Normalised to sum of intensities. 
Added markers from  'mrk' marker vector. Thu Jul 16 22:53:08 2015 
Performed perTurbo prediction (sigma=1 pRegul=0.25) Thu Jul  7 01:45:34 2016 
Added perTurbo predictions according to global threshold = 0.75 Thu Jul  7 01:45:34 2016 
 MSnbase version: 1.17.12 
> plot2D(res, fcol = "perTurbo")
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>