maximum tolerated imbalance in patient numbers during the trial.
p
success probability of the biased coin (e.g. in Efron's Biased Coin
Design).
K
number of treatment groups (e.g. K=2 if we compare one experimental
against one control treatment).
Value
A vector with the allocation sequence for a clinical trial.
It will contain a zero (resp. 1) at position i, when patient i
is allocated to treatment A (resp. B).
References
Chen Yung-Pin (1999) Biased coin design with imbalance tolerance.
Comm. in Stat., 15, 953-975.