Predict allows the user to easily specify which predictors are to
vary. When the vector of values over which a predictor should vary is
not specified, the
range will be all levels of a categorical predictor or equally-spaced
points between the datadist"Low:prediction" and
"High:prediction" values for the variable (datadist by
default uses the 10th smallest and 10th largest predictor values in the
dataset). Predicted values are
the linear predictor (X beta), a user-specified transformation of that
scale, or estimated probability of surviving past a fixed single time
point given the linear predictor. Predict is usually used for
plotting predicted values but there is also a print method.
When the first argument to Predict is a fit object created by
bootcov with coef.reps=TRUE, confidence limits come from
the stored matrix of bootstrap repetitions of coefficients, using
bootstrap percentile nonparametric confidence limits, basic bootstrap,
or BCa limits. Such confidence
intervals do not make distributional assumptions. You can force
Predict to instead use the bootstrap covariance matrix by setting
usebootcoef=FALSE. If coef.reps was FALSE,
usebootcoef=FALSE is the default.
There are ggplot and plot method for Predict
objects that makes it easy to show predicted values and confidence bands.
The rbind method for Predict objects allows you to create
separate sets of predictions under different situations and to combine
them into one set for feeding to plot.Predict. or
ggplot.Predict. For example you
might want to plot confidence intervals for means and for individuals
using ols, and have the two types of confidence bands be
superposed onto one plot or placed into two panels. Another use for
rbind is to combine predictions from quantile regression models
that predicted three different quantiles.
If conf.type="simultaneous", simultaneous (over all requested
predictions) confidence limits are computed. See the
predictrms function for details.
Usage
Predict(x, ..., fun,
type = c("predictions", "model.frame", "x"),
np = 200, conf.int = 0.95,
conf.type = c("mean", "individual","simultaneous"),
usebootcoef=TRUE, boot.type=c("percentile","bca","basic"),
adj.zero = FALSE, ref.zero = FALSE,
kint=NULL, time = NULL, loglog = FALSE, digits=4, name,
factors=NULL, offset=NULL)
## S3 method for class 'Predict'
print(x, ...)
## S3 method for class 'Predict'
rbind(..., rename)
Arguments
x
an rms fit object, or for print the result of Predict.
options(datadist="d") must have been specified (where
d was created by datadist), or
it must have been in effect when the the model was fitted.
...
One or more variables to vary, or single-valued adjustment values.
Specify a variable name without an equal sign to use the default
display range, or any range
you choose (e.g. seq(0,100,by=2),c(2,3,7,14)).
The default list of values for which predictions are made
is taken as the list of unique values of the variable if they number fewer
than 11. For variables with >10 unique values, np
equally spaced values in the range are used for plotting if the
range is not specified. Variables not specified are set to the default
adjustment value limits[2], i.e. the median for continuous
variables and a reference category for non-continuous ones.
Later variables define adjustment settings.
For categorical variables, specify the class labels in quotes when
specifying variable values. If the levels of a categorical variable
are numeric, you may omit the quotes. For variables not described
using datadist, you must specify explicit ranges and
adjustment settings for predictors that were in the model.
If no variables are specified in ..., predictions will be made by
separately varying all predictors in the model over their default
range, holding the other predictors at their adjustment values.
This has the same effect as specifying name as a vector
containing all the predictors. For rbind, ... represents a
series of results from Predict. If you name the results,
these names will be taken as the values of the new .set.
variable added to the concatenated data frames. See an example below.
fun
an optional transformation of the linear predictor.
Specify fun='mean' if the fit is a proportional odds model
fit and you ran bootcov with coef.reps=TRUE. This
will let the mean function be re-estimated for each bootstrap rep to
properly account for all sources of uncertainty in estimating the
mean response.
type
defaults to providing predictions. Set to "model.frame" to
return a data frame of predictor settings used. Set to "x"
to return the corresponding design matrix constructed from the
predictor settings.
np
the number of equally-spaced points computed for continuous
predictors that vary, i.e., when the specified value is .
or NA
conf.int
confidence level. Default is 0.95. Specify FALSE to suppress.
conf.type
type of confidence interval. Default is "mean" which applies
to all models. For models containing a residual variance (e.g,
ols), you can specify conf.type="individual" instead,
to obtain limits on the predicted value for an individual subject.
Specify conf.type="simultaneous" to obtain simultaneous
confidence bands for mean predictions with family-wise coverage of
conf.int.
usebootcoef
set to FALSE to force the use of the bootstrap
covariance matrix estimator even when bootstrap coefficient reps are
present
boot.type
set to 'bca' to compute BCa confidence
limits or 'basic' to use the basic bootstrap. The default is
to compute percentile intervals
adj.zero
Set to TRUE to adjust all non-plotted variables to 0 (or
reference cell for categorical variables) and to omit intercept(s)
from consideration. Default is FALSE.
ref.zero
Set to TRUE to subtract a constant from X beta
before plotting so that the reference value of the x-variable
yields y=0. This is done before applying function fun.
This is especially useful for Cox models to make the hazard ratio be
1.0 at reference values, and the confidence interval have width zero.
kint
This is only useful in a multiple intercept model such as the ordinal
logistic model. There to use to second of three intercepts, for example,
specify kint=2. The default is 1 for lrm and the middle
intercept corresponding to the median y for orm.
time
Specify a single time u to cause function survest to
be invoked to plot the probability of surviving until time u
when the fit is from cph or psm.
loglog
Specify loglog=TRUE to plot log[-log(survival)]
instead of survival, when time is given.
digits
Controls how “adjust-to” values are plotted. The default is 4
significant digits.
name
Instead of specifying the variables to vary in the
variables (...) list, you can specify one or more variables
by specifying a vector of character string variable names in the
name argument. Using this mode you cannot specify a list of
variable values to use; prediction is done as if you had said e.g.
age without the equal sign. Also, interacting factors can
only be set to their reference values using this notation.
factors
an alternate way of specifying ..., mainly for use by
survplot or gendata. This must be a list with one or
more values for each variable listed, with NA values for
default ranges.
offset
a list containing one value for one variable, which is
mandatory if the model included an offset term. The variable name
must match the innermost variable name in the offset term. The
single offset is added to all predicted values.
rename
If you are concatenating predictor sets using rbind and one
or more of the variables were renamed for one or more of the sets,
but these new names represent different versions of the same
predictors (e.g., using or not using imputation), you can specify a
named character vector to rename predictors to a central name. For
example, specify rename=c(age.imputed='age',
corrected.bp='bp') to rename from old names age.imputed,
corrected.bp to age, bp. This happens before
concatenation of rows.
Details
When there are no intercepts in the fitted model, plot subtracts
adjustment values from each factor while computing variances for
confidence limits.
Specifying time will not work for Cox models with time-dependent
covariables. Use survest or survfit for that purpose.
Value
a data frame containing all model predictors and the computed values
yhat, lower, upper, the latter two if confidence
intervals were requested. The data frame has an additional
class"Predict". If name is specified or no
predictors are specified in ..., the resulting data frame has an
additional variable called .predictor. specifying which
predictor is currently being varied. .predictor. is handy for
use as a paneling variable in lattice or ggplot2 graphics.
Author(s)
Frank Harrell
Department of Biostatistics, Vanderbilt University
f.harrell@vanderbilt.edu
n <- 1000 # define sample size
set.seed(17) # so can reproduce the results
age <- rnorm(n, 50, 10)
blood.pressure <- rnorm(n, 120, 15)
cholesterol <- rnorm(n, 200, 25)
sex <- factor(sample(c('female','male'), n,TRUE))
label(age) <- 'Age' # label is in Hmisc
label(cholesterol) <- 'Total Cholesterol'
label(blood.pressure) <- 'Systolic Blood Pressure'
label(sex) <- 'Sex'
units(cholesterol) <- 'mg/dl' # uses units.default in Hmisc
units(blood.pressure) <- 'mmHg'
# Specify population model for log odds that Y=1
L <- .4*(sex=='male') + .045*(age-50) +
(log(cholesterol - 10)-5.2)*(-2*(sex=='female') + 2*(sex=='male'))
# Simulate binary y to have Prob(y=1) = 1/[1+exp(-L)]
y <- ifelse(runif(n) < plogis(L), 1, 0)
ddist <- datadist(age, blood.pressure, cholesterol, sex)
options(datadist='ddist')
fit <- lrm(y ~ blood.pressure + sex * (age + rcs(cholesterol,4)))
Predict(fit, age, cholesterol, np=4)
Predict(fit, age=seq(20,80,by=10), sex, conf.int=FALSE)
Predict(fit, age=seq(20,80,by=10), sex='male') # works if datadist not used
# Get simultaneous confidence limits accounting for making 7 estimates
# Predict(fit, age=seq(20,80,by=10), sex='male', conf.type='simult')
# (this needs the multcomp package)
ddist$limits$age[2] <- 30 # make 30 the reference value for age
# Could also do: ddist$limits["Adjust to","age"] <- 30
fit <- update(fit) # make new reference value take effect
Predict(fit, age, ref.zero=TRUE, fun=exp)
# Make two curves, and plot the predicted curves as two trellis panels
w <- Predict(fit, age, sex)
require(lattice)
xyplot(yhat ~ age | sex, data=w, type='l')
# To add confidence bands we need to use the Hmisc xYplot function in
# place of xyplot
xYplot(Cbind(yhat,lower,upper) ~ age | sex, data=w,
method='filled bands', type='l', col.fill=gray(.95))
# If non-displayed variables were in the model, add a subtitle to show
# their settings using title(sub=paste('Adjusted to',attr(w,'info')$adjust),adj=0)
# Easier: feed w into plot.Predict
## Not run:
# Predictions form a parametric survival model
n <- 1000
set.seed(731)
age <- 50 + 12*rnorm(n)
label(age) <- "Age"
sex <- factor(sample(c('Male','Female'), n,
rep=TRUE, prob=c(.6, .4)))
cens <- 15*runif(n)
h <- .02*exp(.04*(age-50)+.8*(sex=='Female'))
t <- -log(runif(n))/h
label(t) <- 'Follow-up Time'
e <- ifelse(t<=cens,1,0)
t <- pmin(t, cens)
units(t) <- "Year"
ddist <- datadist(age, sex)
Srv <- Surv(t,e)
# Fit log-normal survival model and plot median survival time vs. age
f <- psm(Srv ~ rcs(age), dist='lognormal')
med <- Quantile(f) # Creates function to compute quantiles
# (median by default)
Predict(f, age, fun=function(x)med(lp=x))
# Note: This works because med() expects the linear predictor (X*beta)
# as an argument. Would not work if use
# ref.zero=TRUE or adj.zero=TRUE.
# Also, confidence intervals from this method are approximate since
# they don't take into account estimation of scale parameter
# Fit an ols model to log(y) and plot the relationship between x1
# and the predicted mean(y) on the original scale without assuming
# normality of residuals; use the smearing estimator. Before doing
# that, show confidence intervals for mean and individual log(y),
# and for the latter, also show bootstrap percentile nonparametric
# pointwise confidence limits
set.seed(1)
x1 <- runif(300)
x2 <- runif(300)
ddist <- datadist(x1,x2); options(datadist='ddist')
y <- exp(x1+ x2 - 1 + rnorm(300))
f <- ols(log(y) ~ pol(x1,2) + x2, x=TRUE, y=TRUE) # x y for bootcov
fb <- bootcov(f, B=100)
pb <- Predict(fb, x1, x2=c(.25,.75))
p1 <- Predict(f, x1, x2=c(.25,.75))
p <- rbind(normal=p1, boot=pb)
plot(p)
p1 <- Predict(f, x1, conf.type='mean')
p2 <- Predict(f, x1, conf.type='individual')
p <- rbind(mean=p1, individual=p2)
plot(p, label.curve=FALSE) # uses superposition
plot(p, ~x1 | .set.) # 2 panels
r <- resid(f)
smean <- function(yhat)smearingEst(yhat, exp, res, statistic='mean')
formals(smean) <- list(yhat=numeric(0), res=r[!is.na(r)])
#smean$res <- r[!is.na(r)] # define default res argument to function
Predict(f, x1, fun=smean)
## Example using offset
g <- Glm(Y ~ offset(log(N)) + x1 + x2, family=poisson)
Predict(g, offset=list(N=100))
## End(Not run)
options(datadist=NULL)