Comparison between overall survival and disease-free survival for prostate cancer

Description

Results from five randomized clinical trials published between 1988 and 2011

Format

The data frame contains the following columns:

y1

log-hazard ratio estimates comparing combined therapy using Goserelin acetate with radiotherapy with respect to overall survival

s1

within-study standard error for outcome 1

y2

log-hazard ratio estimates comparing combined therapy using Goserelin acetate with radiotherapy with respect to disease-free survival

s2

within-study stamdard error for outcome 2

Note

The dataset prostate is used to conduct bivariate random-effects meta-analysis when the within-study correlations are unknown.

References

Chen, Y., Hong, C. and Riley, R. D. (2015). An alternative pseudolikelihood method for multivariate random-effects meta-analysis. Statistics in medicine, 34(3), 361-380.

Sasse A, Sasse E, Carvalho A, Macedo L. Androgenic suppression combined with radiotherapy for the treatment of prostate adenocarcinoma: a systematic review. BMC cancer 2012; 12(1):54. 30.

See Also

mmeta, summary.mmeta

Examples

data(prostate)
summary(prostate)

Results