GeneDropSim.fn
(Package: RVsharing) :
Estimation of the probability of sharing of a rare variant by gene dropping in a pedigree
Estimates the probability that all subjects in a set of pedigree members share a rare variant given that it occured in any of them by performing a Monte Carlo simulation of the transmission of the genotypes of the variant from the founders down the pedigree.
get.psubset
(Package: RVsharing) :
Probability of sharing of rare variants in a subset of families
Computing probability of sharing of rare variants in a subset of families where rare variants are seen based on precomputed family-specific rare variant sharing probabilities.
Estimates the probability that all subjects in a subset of pedigree members share a rare variant (RV) given that it occured in any of them by performing a Monte Carlo simulation of the transmission of the genotypes of the variant from the founders down the pedigree.
GeneDropSim.allsubsets.fn
(Package: RVsharing) :
Estimation of the probability of sharing of a rare variant by gene dropping in a pedigree
Estimates the probabilities of sharing a rare variant for all subsets of a given set of pedigree members given that the rare variant occured in any subject in the set by performing a Monte Carlo simulation of the transmission of the genotypes of the variant from the founders down the pedigree.
RVsharing
(Package: RVsharing) :
Probability of sharing a rare variant among relatives
Computing probability that a rare variant is shared by a set of subjects in a pedigree using equation (1) of Bureau et al. and a generalization to a subset of subjects.