Last data update: 2014.03.03

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golub.pval (Package: LBE) : p-values corresponding to the gene expression data from Golub et al. (1999).

The aim of the study of Golub et al. Golub was to identify differentially expressed genes between acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The samples were assayed using Affymetrix Hgu6800 chips and the data on the expression of 7129 genes are available in the Bioconductor package golubEsets. The p-values provided here were calculated from a two-sample t-test analysis. The variance-stabilizing method included in the vsn package was applied for normalizing the data.
● Data Source: BioConductor
● Keywords: datasets
● Alias: golub.pval
● 0 images

hedenfalk.pval (Package: LBE) : p-values corresponding to the gene expression data from Hedenfalk et al. (2001).

The aim of the study of Hedenfalk et al. (2001) was to examine breast-cancer tissues from patients with BRCA1-BRCA2 related cancer and cases of sporadic breast cancer to determine global gene expression patterns in the different classes of tumours. Here, we focus on the comparison of BRCA1 and BRCA2. The p-values provided here are the same as those provided with the package qvalue. They were otained from a two-sample t-test analysis on a subset of 3,170 genes, as described in Storey and Tibshirani (2003).
● Data Source: BioConductor
● Keywords: datasets
● Alias: hedenfalk.pval
● 0 images