FDb.InfiniumMethylation.hg19 is an omnibus package that merges all of the existing Illumina Infinium DNA methylation probe annotations into one FDb. However, most users will be analyzing one of the two chips at any given time. The utility functions getPlatform(platform), get450k(), and get27k() retrieve a compact GenomicRanges form of the annotations for the requested platform.
In the subdirectory inst/build/, there are several scripts that rebuild this FeatureDb from scratch. A handful of intermediate results from dbSNP and comparison of existing datasets are required to patch small gaps in the Illumina manifests. These datasets supply those intermediate results.
● Data Source:
BioConductor
● Keywords: data
● Alias: SNPs.hg18, hg18ToHg19, hm27.SNP.colors, hm27.controls, hm450.controls, hm450k.rsProbes, unmappable
●
0 images
This package loads one or more FeatureDb objects. Such FeatureDb objects are an R interface to prefabricated databases contained by this package. In the case of the Infinium methylation FDb, it is FDb.InfiniumMethylation.hg18 (for the moment; hg18 may come later, or alternatively users can use liftOver() from rtracklayer to do it).