Surrogate

Package: Surrogate
Type: Package
Title: Evaluation of Surrogate Endpoints in Clinical Trials
Version: 0.1-73
Date: 2016-05-16
Author: Wim Van der Elst, Paul Meyvisch, Ariel Alonso, Hannah M. Ensor, Christopher J. Weir & Geert Molenberghs
Maintainer: Wim Van der Elst <Wim.vanderelst@gmail.com>
Description: In a clinical trial, it frequently occurs that the most credible outcome to evaluate the effectiveness of a new therapy (the true endpoint) is difficult to measure. In such a situation, it can be an effective strategy to replace the true endpoint by a (bio)marker that is easier to measure and that allows for a prediction of the treatment effect on the true endpoint (a surrogate endpoint). The package 'Surrogate' allows for an evaluation of the appropriateness of a candidate surrogate endpoint based on the meta-analytic, information-theoretic, and causal-inference frameworks. Part of this software has been developed using funding provided from the European Union's 7-th Framework Programme for research, technological development and demonstration under Grant Agreement no 602552.
Depends: MASS, msm
Imports: rgl, lattice, latticeExtra, survival, nlme, lme4,
OrdinalLogisticBiplot, logistf, rms, mixtools
License: GPL (>= 2)
BugReports: Wim Van der Elst <Wim.vanderelst@gmail.com>
Repository: CRAN
NeedsCompilation: no
Packaged: 2016-05-16 07:14:28 UTC; WimVDE
Date/Publication: 2016-05-16 14:33:06

Install log

* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'Surrogate' ...
** package 'Surrogate' successfully unpacked and MD5 sums checked
** R
** data
** preparing package for lazy loading
** help
*** installing help indices
  converting help for package 'Surrogate'
    finding HTML links ... done
    ARMD                                    html  
    BifixedContCont                         html  
    BimixedContCont                         html  
    CIGTS                                   html  
    CausalDiagramBinBin                     html  
    CausalDiagramContCont                   html  
    FixedBinBinIT                           html  
    FixedBinContIT                          html  
    FixedContBinIT                          html  
    FixedContContIT                         html  
    FixedDiscrDiscrIT                       html  
    finding level-2 HTML links ... done

    ICA.BinBin.Grid.Full                    html  
    ICA.BinBin.Grid.Sample                  html  
    ICA.BinBin.Grid.Sample.Uncert           html  
    ICA.Sample.ContCont                     html  
    ICABinBin                               html  
    ICABinBinCounterAssum                   html  
    ICABinCont                              html  
    ICAContCont                             html  
    LongToWide                              html  
    MICA.Sample.ContCont                    html  
    MICAContCont                            html  
    MarginalProbs                           html  
    MaxEntICABinBin                         html  
    MaxEntSPFBinBin                         html  
    MinSurrContCont                         html  
    MixedContContIT                         html  
    Ovarian                                 html  
    Plot.FixedDiscrDiscrIT                  html  
    Plot.PredTrialTContCont                 html  
    Pos.Def.Matrices                        html  
    Pred.TrialT.ContCont                    html  
    Prentice                                html  
    RandVec                                 html  
    Restrictions.BinBin                     html  
    SPP.BinBin                              html  
    Schizo                                  html  
    Schizo_Bin                              html  
    Schizo_PANSS                            html  
    Sim.Data.Counterfactuals                html  
    Sim.Data.CounterfactualsBinBin          html  
    Sim.Data.MTS                            html  
    Sim.Data.STS                            html  
    Sim.Data.STSBinBin                      html  
    Single.Trial.RE.AA                      html  
    SurvSurv                                html  
    Test.Mono                               html  
    TrialLevelIT                            html  
    TrialLevelMA                            html  
    TwoStageSurvSurv                        html  
    UnifixedContCont                        html  
    UnimixedContCont                        html  
    plot.CausalInference                    html  
    plot.ICABinBin                          html  
    plot.ICABinCont                         html  
    plot.InformationTheoretic               html  
    plot.InformationTheoreticBinCombn       html  
    plot.InformationTheoreticSurvSurv       html  
    plot.MaxEntICABinBin                    html  
    plot.MaxEntSPFBinBin                    html  
    plot.MetaAnalytic                       html  
    plot.MinSurrContCont                    html  
    plot.SPPBinBin                          html  
    plot.TrialLevelIT                       html  
    plot.TrialLevelMA                       html  
    plot.TwoStageSurvSurv                   html  
    summary.gen                             html  
** building package indices
** testing if installed package can be loaded
* DONE (Surrogate)
Making 'packages.html' ... done