The data consist of 15 human cell strains with known karyotype (12 fibroblast cell strains, 2 chorionic villus cell strains, 1 lymploblast cell strain) from the NIGMS Human Genetics Cell Repository (http://locus.umdnj.edu/nigms). Each cell strain has been hybridized onto a CGH-array of 2276 BAC's spotted in triplicate.
A M Snijders, N Nowak, R Segraves, S Blackwood, N Brown, J
Conroy, G Hamilton, A K Hindle, B Huey, K Kimura, S Law, K Myambo, J
Palmer, B Ylstra, J P Yue, J W Gray, A N Jain, D Pinkel & D G
Albertson , Assembly of microarrays for genome-wide measurement of
DNA copy number,
Nature Genetics 29, pp 263 - 264 (2001) Brief Communications.
Examples
data(snijders)
array <- gm13330
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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Platform: x86_64-pc-linux-gnu (64-bit)
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> library(GLAD)
######################################################################################
Have fun with GLAD
For smoothing it is possible to use either
the AWS algorithm (Polzehl and Spokoiny, 2002,
or the HaarSeg algorithm (Ben-Yaacov and Eldar, Bioinformatics, 2008,
If you use the package with AWS, please cite:
Hupe et al. (Bioinformatics, 2004, and Polzehl and Spokoiny (2002,
If you use the package with HaarSeg, please cite:
Hupe et al. (Bioinformatics, 2004, and (Ben-Yaacov and Eldar, Bioinformatics, 2008,
For fast computation it is recommanded to use
the daglad function with smoothfunc=haarseg
######################################################################################
New options are available in daglad: see help for details.
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/GLAD/snijders.Rd_%03d_medium.png", width=480, height=480)
> ### Name: snijders
> ### Title: Public CGH data of Snijders
> ### Aliases: gm00143 gm01524 gm01535 gm01750 gm02948 gm03134 gm03563
> ### gm03576 gm04435 gm05296 gm07081 gm07408 gm10315 gm13031 gm13330
> ### Keywords: datasets
>
> ### ** Examples
>
> data(snijders)
> array <- gm13330
>
>
>
>
>
> dev.off()
null device
1
>