R: Remission Times for Acute Myelogenous Leukaemia
aml
R Documentation
Remission Times for Acute Myelogenous Leukaemia
Description
The aml data frame has 23 rows and 3 columns.
A clinical trial to evaluate the efficacy of maintenance chemotherapy for
acute myelogenous leukaemia was
conducted by Embury et al. (1977) at Stanford University. After reaching a
stage of remission through treatment by chemotherapy, patients were randomized
into two groups. The first group received maintenance chemotherapy and the
second group did not. The aim of the study was to see if maintenance
chemotherapy increased the length of the remission. The data here formed a
preliminary analysis which was conducted in October 1974.
Usage
aml
Format
This data frame contains the following columns:
time
The length of the complete remission (in weeks).
cens
An indicator of right censoring. 1 indicates that the patient had a relapse
and so time is the length of the remission. 0 indicates that the patient
had left the study or was still in remission in October 1974, that is the
length of remission is right-censored.
group
The group into which the patient was randomized. Group 1 received
maintenance chemotherapy, group 2 did not.
Note
Package boot also has the dataset aml.
Source
The data were obtained from
Miller, R.G. (1981) Survival Analysis. John Wiley.
References
Davison, A.C. and Hinkley, D.V. (1997)
Bootstrap Methods and Their Application. Cambridge University Press.
Embury, S.H, Elias, L., Heller, P.H., Hood, C.E., Greenberg, P.L. and
Schrier, S.L. (1977) Remission maintenance therapy in acute myelogenous
leukaemia. Western Journal of Medicine, 126, 267-272.