Last data update: 2014.03.03

R: Lymphoma Gene Expression Dataset
lymphomaR Documentation

Lymphoma Gene Expression Dataset

Description

This dataset consists of gene expression profiles of the three most prevalent adult lymphoid malignancies: diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and B-cell chronic lymphocytic leukemia (B-CLL). The dataset consists of 4,682 genes in 62 mRNA samples: 42 samples of DLBCL, 9 samples of FL, and 11 samples. of B-CLL. Missing value are imputed and data are standardized as described in Dudoit, et al. (2002).

Usage

data(lymphoma)

Value

A list with the following elements:

data

Gene expression data. A matrix with 62 rows and 4,682 columns.

class

Class index. A vector with 62 elements.

References

Alizadeh AA, Eisen MB, Davis RE, et al.
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
Nature 2000;403(6769):503-511.

Dudoit S, Fridlyand J, Speed TP.
Comparison of discrimination methods for the classification of tumors using gene expression data.
J Am Stat Assoc 2002;97(417):77-87.

Examples

data(lymphoma)
class=1+as.numeric(as.factor(unlist(lymphoma$class)))
cc=cmdscale(dist(lymphoma$data))
plot(cc,pch=21,bg=class,xlab="First Component",ylab="Second Component");

# WARNING: The next example is high computational extensive
#
# kk=KODAMA(lymphoma$data,FUN=PLS.SVM.CV)
# cc=cmdscale(kk$dissimilarity)
# plot(cc,pch=21,bg=class,xlab="First Component",ylab="Second Component");

Results


R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(KODAMA)
Loading required package: e1071
Loading required package: plsgenomics
Loading required package: MASS
Loading required package: boot
Loading required package: parallel
Loading required package: class

Attaching package: 'KODAMA'

The following object is masked from 'package:plsgenomics':

    transformy

> png(filename="/home/ddbj/snapshot/RGM3/R_CC/result/KODAMA/lymphoma.Rd_%03d_medium.png", width=480, height=480)
> ### Name: lymphoma
> ### Title: Lymphoma Gene Expression Dataset
> ### Aliases: lymphoma
> ### Keywords: datasets
> 
> ### ** Examples
> 
> data(lymphoma)
> class=1+as.numeric(as.factor(unlist(lymphoma$class)))
> cc=cmdscale(dist(lymphoma$data))
> plot(cc,pch=21,bg=class,xlab="First Component",ylab="Second Component");
> 
> # WARNING: The next example is high computational extensive
> #
> # kk=KODAMA(lymphoma$data,FUN=PLS.SVM.CV)
> # cc=cmdscale(kk$dissimilarity)
> # plot(cc,pch=21,bg=class,xlab="First Component",ylab="Second Component");
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>