Custom capture array design

Description

Design of a custom Roche NimbleGen 385k capture array. The array captures short segments corresponding to all exon regions of 92 distinct target genes (genome build hg19). In addition, contiguous genomic regions were represented for three additional genes, i.e. CBFB, MLL, and RUNX1.

Usage

data(captureArray)

Format

Formal class 'CompressedIRangesList'

Source

‘Targeted next-generation sequencing detects point mutations, insertions, deletions, and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure’ (Leukemia, submitted)

Examples

data(captureArray)

Results

R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

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> library(R453Plus1Toolbox)
Loading required package: VariantAnnotation
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
    get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
    rbind, rownames, sapply, setdiff, sort, table, tapply, union,
    unique, unsplit

Loading required package: GenomeInfoDb
Loading required package: stats4
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    colMeans, colSums, expand.grid, rowMeans, rowSums

Loading required package: IRanges
Loading required package: GenomicRanges
Loading required package: SummarizedExperiment
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: Rsamtools
Loading required package: Biostrings
Loading required package: XVector

Attaching package: 'VariantAnnotation'

The following object is masked from 'package:base':

    tabulate

> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/R453Plus1Toolbox/captureArray.Rd_%03d_medium.png", width=480, height=480)
> ### Name: captureArray
> ### Title: Custom capture array design
> ### Aliases: captureArray
> ### Keywords: datasets
> 
> ### ** Examples
> 
> data(captureArray)
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>