Returns a matrix of 'Specificity scores' (S) defined as 1-JSD(p_g,q_i) where p_g is the Log10+1 expression profile of a gene g across all conditions j, collapsed into a probability distribution,
and q_i is the unit vector of 'perfect expression' in a given condition i.
Usage
## S4 method for signature 'CuffFeatureSet'
csSpecificity(object,logMode=T,pseudocount=1,relative=FALSE,...)
## S4 method for signature 'CuffData'
csSpecificity(object,logMode=T,pseudocount=1,relative=FALSE,...)
Arguments
object
An object of class CuffFeatureSet, CuffGeneSet, or CuffData.
logMode
A logical argument to log10-transform FPKM values prior to plotting.
pseudocount
Value to be added to FPKM for appropriate log transformation and clustering. (Avoids zero-based errors)
relative
A logical argument that when TRUE, will scale the S values from 0-1 by dividing by max(S)
...
Additional arguments to fpkmMatrix.
Details
None
Author(s)
Loyal A. Goff
Source
None
References
None.
Examples
data(sampleData)
csSpecificity(sampleGeneSet)
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
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> library(cummeRbund)
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Loading required package: RSQLite
Loading required package: DBI
Loading required package: ggplot2
Loading required package: reshape2
Loading required package: fastcluster
Attaching package: 'fastcluster'
The following object is masked from 'package:stats':
hclust
Loading required package: rtracklayer
Loading required package: GenomicRanges
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: 'S4Vectors'
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: Gviz
Loading required package: grid
Attaching package: 'cummeRbund'
The following object is masked from 'package:GenomicRanges':
promoters
The following object is masked from 'package:IRanges':
promoters
The following object is masked from 'package:BiocGenerics':
conditions
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/cummeRbund/csSpecificity.Rd_%03d_medium.png", width=480, height=480)
> ### Name: csSpecificity
> ### Title: csSpecificity
> ### Aliases: csSpecificity csSpecificity,CuffFeatureSet-method
> ### csSpecificity,CuffData-method
> ### Keywords: datasets
>
> ### ** Examples
>
> data(sampleData)
> csSpecificity(sampleGeneSet)
Using tracking_id, sample_name as id variables
iPS_spec hESC_spec Fibroblasts_spec
XLOC_000069 0.3404865 5.281363e-01 0.03949159
XLOC_000089 0.2843602 3.315380e-01 0.35041646
XLOC_000105 0.3006743 3.138327e-01 0.35217793
XLOC_000115 1.0000000 0.000000e+00 0.00000000
XLOC_000132 0.2940644 3.073414e-01 0.36481155
XLOC_000151 0.4977991 3.247807e-01 0.11444635
XLOC_000158 0.2405263 6.483151e-01 0.00000000
XLOC_000170 0.2102559 5.488920e-01 0.18734324
XLOC_001240 0.3011602 3.143650e-01 0.35118948
XLOC_001262 0.2809749 3.504865e-01 0.33471435
XLOC_001263 0.2832491 3.344485e-01 0.34859109
XLOC_001265 0.2596253 3.892470e-01 0.31531604
XLOC_001297 0.0000000 3.416102e-01 0.54346293
XLOC_001339 0.3365391 3.265969e-01 0.30384333
XLOC_001348 0.7079814 1.110223e-16 0.18534248
XLOC_001359 0.3093951 3.090976e-01 0.34833884
XLOC_001363 1.0000000 0.000000e+00 0.00000000
XLOC_001369 0.3222189 3.274421e-01 0.31750748
XLOC_001370 0.2880325 3.117768e-01 0.36625945
XLOC_001411 0.3426006 3.485996e-01 0.27467945
>
>
>
>
>
> dev.off()
null device
1
>