Comprehensive protein-protein interaction maps promise to reveal many
aspects of the complex regulatory network underlying cellular
function.
This data set was compiled by von Mering et al. (see reference below),
combining various sources. Only the interactions that have
‘high’ and ‘medium’ confidence are included here.
Usage
yeast
Format
An undirected igraph graph object. Its graph attributes:
‘name’, ‘Citation’, ‘Author’,
‘URL’. ‘Classes’. The ‘Classes’
attribute contain the key for the classification labels of the
proteins, in a data frame, the original MIPS categories are given
after the semicolon:
E
energy production; energy
G
aminoacid metabolism; aminoacid metabolism
M
other metabolism; all remaining metabolism categories
P
translation; protein synthesis
T
transcription; transcription, but without subcategory
‘transcriptional control’
Comparative assessment of large-scale data sets of protein-protein
interactions. Christian von Mering, Roland Krause, Berend Snel,
Michael Cornell, Stephen G. Oliver, Stanley Fields and Peer
Bork. Nature 417, 399-403 (2002)