A sample microRNA expression profiling data using miRCURY LNA
microRNA Array based on miRbase 9.2 (Exiqon Inc., Denmark) for 40
human osteosarcoma xenograft specimens, including 10 samples for each
chemotherapeutic treatment (Cisplatin, Doxorubicin, and Ifosfamide)
plus 10 non-treated samples.
Usage
data(OX40Exiqon)
Format
A data frame with 168192 rows and 7 columns (variables).
Gene
character
MicroRNA names.
Flag
numeric
an indictor showing the probe signal quality.
Repeat
numeric
an indictor showing the technical replicates.
Treat
numeric
treatment type: coded.
Sample
numeric
sample id.
Signal
numeric
fluorescence intensity measures
Background
numeric
measures of background noises
References
Wang, B., Zhang, S-G., Wang, X-F., Tan, M. and Xi, Y. (2012) "Testing
for differentially-expressed microRNAs with errors-in-variables
nonparametric regression", PLoS ONE 7(5):
e37537. doi:10.1371/journal.pone.0037537.
Wang, B., Wang, X-F. and Xi, Y. (2011) "Normalizing bead-based
microRNA expression data: a measurement error model-based approach",
Bioinformatics, 27(11), 1506-1512.
Wang, B., Howell, P., Bruheim, S. Ju, J, Owen, L.B., Fodstad, O. and
Xi, Y. (2011). "Systematic Evaluation of Three microRNA Profiling
Platforms: Microarray, Beads Array, and Quantitative Real-Time PCR
Array", PLoS ONE 6(2): e17167.
Wang, B. and Wertelecki, W. (2012) "Density Estimation for Data With
Rounding Errors", Computational Statistics and Data Analysis, (in
press). doi: 10.1016/j.csda.2012.02.016. link
Wang, B., Wang, X-F. and Xi, Y. (2011) "Normalizing bead-based
microRNA expression data: a measurement error model-based approach",
Bioinformatics, 27(11), 1506-1512.
Wang, X-F. and Wang, B. (2011) "Deconvolution Estimation in
Measurement Error Models: The R Package decon", Journal of Statistical
Software, 39(10), 1-24.
Examples
data(OX40Exiqon)
ex = structure(list(x = ox40ex92), class='exiqon')
print(ex)