Microarray gene expression profiles of the NCI 60 cell lines from 4 different platforms

Description

The 60 human tumour cell lines are derived from patients with leukaemia, melanoma, lung, colon, central nervous system, ovarian, renal, breast and prostate cancers. The cell line panel is widely used in anti-cancer drug screen. In this dataset, a subset of microarray gene expression of the NCI 60 cell lines from four different platforms are combined in a list, which could be used as input to mcia directly.

Usage

data(NCI60_4arrays)

Format

The format is: List of 4 data.frames

• $agilent:data.frame containing 300 rows and 60 columns. 300 gene expression log ratio measurements of the NCI60 cell lines, by Agilent platform.

• $hgu133:data.frame containing 298 rows and 60 columns. 298 gene expression log ratio measurements of the NCI60 cell lines, by H-GU133 platform.

• $hgu133p2:data.frame containing 268 rows and 60 columns. 268 gene expression log ratio measurements of the NCI60 cell lines, by H-GU133 plus 2.0 platform.

• $hgu95:data.frame containing 288 rows and 60 columns. 288 gene expression log ratio measurements of the NCI60 cell lines, by H-GU95 platform.

Source

Cell Miner http://discover.nci.nih.gov/cellminer/

References

Reinhold WC, Sunshine M, Liu H, Varma S, Kohn KW, Morris J, Doroshow J, Pommier Y CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set. Cancer Research. 2012 Jul, 15;72(14):3499-511

Examples

data(NCI60_4arrays)
summary(NCI60_4arrays)
mcoin <- mcia(NCI60_4arrays)

Results

R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

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> library(omicade4)
Loading required package: ade4
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/omicade4/NCI60_4arrays.Rd_%03d_medium.png", width=480, height=480)
> ### Name: NCI60_4arrays
> ### Title: Microarray gene expression profiles of the NCI 60 cell lines
> ###   from 4 different platforms
> ### Aliases: NCI60_4arrays
> ### Keywords: datasets NCI-60 Microarray
> 
> ### ** Examples
> 
> data(NCI60_4arrays)
> summary(NCI60_4arrays)
         Length Class      Mode
agilent  60     data.frame list
hgu133   60     data.frame list
hgu133p2 60     data.frame list
hgu95    60     data.frame list
> mcoin <- mcia(NCI60_4arrays)
> 
> 
> 
> 
> 
> dev.off()
null device 
          1 
>