R: Map between Entrez Gene IDs and Enzyme Commission (EC)...
org.Mm.egENZYME
R Documentation
Map between Entrez Gene IDs and Enzyme Commission (EC) Numbers
Description
org.Mm.egENZYME is an R object that provides mappings between
entrez gene identifiers and EC numbers.
Details
Each entrez gene identifier maps to a named vector containing the EC number that
corresponds to the enzyme produced by that gene. The name corresponds
to the entrez gene identifier. If this information is unknown, the vector
will contain an NA.
Enzyme Commission numbers are assigned by the Nomenclature Committee
of the International Union of Biochemistry and Molecular Biology
http://www.chem.qmw.ac.uk/iubmb/enzyme/ to allow enzymes to be
identified.
An Enzyme Commission number is of the format EC x.y.z.w, where x, y, z,
and w are numeric numbers. In org.Mm.egENZYME2EG, EC is dropped from the
Enzyme Commission numbers.
Enzyme Commission numbers have corresponding names that describe the
functions of enzymes in such a way that EC x is a more general
description than EC x.y that in turn is a more general description than
EC x.y.z. The top level EC numbers and names are listed below:
Mappings between entrez gene identifiers and enzyme identifiers were obtained using files
provided by: KEGG GENOME
ftp://ftp.genome.jp/pub/kegg/genomes
With a date stamp from the source of: 2011-Mar15
For the reverse map, each EC number maps to a named vector containing
the entrez gene identifier that corresponds to the gene that produces
that enzyme. The name of the vector corresponds to the EC number.
AnnotationDb-class for use of
the select() interface.
Examples
## select() interface:
## Objects in this package can be accessed using the select() interface
## from the AnnotationDbi package. See ?select for details.
## Bimap interface:
x <- org.Mm.egENZYME
# Get the entrez gene identifiers that are mapped to an EC number
mapped_genes <- mappedkeys(x)
# Convert to a list
xx <- as.list(x[mapped_genes])
if(length(xx) > 0) {
# Get the ENZYME for the first five genes
xx[1:5]
# Get the first one
xx[[1]]
}
# For the reverse map:
# Convert to a list
xx <- as.list(org.Mm.egENZYME2EG)
if(length(xx) > 0){
# Gets the entrez gene identifiers for the first five enzyme
#commission numbers
xx[1:5]
# Get the first one
xx[[1]]
}
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
Copyright (C) 2016 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)
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Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
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Type 'q()' to quit R.
> library(org.Mm.eg.db)
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: IRanges
Loading required package: S4Vectors
Attaching package: 'S4Vectors'
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/org.Mm.eg.db/org.Mm.egENZYME.Rd_%03d_medium.png", width=480, height=480)
> ### Name: org.Mm.egENZYME
> ### Title: Map between Entrez Gene IDs and Enzyme Commission (EC) Numbers
> ### Aliases: org.Mm.egENZYME org.Mm.egENZYME2EG
> ### Keywords: datasets
>
> ### ** Examples
>
> ## select() interface:
> ## Objects in this package can be accessed using the select() interface
> ## from the AnnotationDbi package. See ?select for details.
>
> ## Bimap interface:
> x <- org.Mm.egENZYME
> # Get the entrez gene identifiers that are mapped to an EC number
> mapped_genes <- mappedkeys(x)
> # Convert to a list
> xx <- as.list(x[mapped_genes])
> if(length(xx) > 0) {
+ # Get the ENZYME for the first five genes
+ xx[1:5]
+ # Get the first one
+ xx[[1]]
+ }
[1] "2.3.1.87"
> # For the reverse map:
> # Convert to a list
> xx <- as.list(org.Mm.egENZYME2EG)
> if(length(xx) > 0){
+ # Gets the entrez gene identifiers for the first five enzyme
+ #commission numbers
+ xx[1:5]
+ # Get the first one
+ xx[[1]]
+ }
[1] "11298"
>
>
>
>
>
> dev.off()
null device
1
>