matrix with data coming from differentiated and undifferentiated human HepaRG cells
Usage
data(tRanslatomeSampleData)
Format
tRanslatomeSampleData is a list that has 7 components :
expressionMatrix is a matrix of 12 columns and 1000 rows containing the microarray signals used as input of the function GetDEGs. Columns are organized in biological triplicates as follows:
tot.diff.a, tot.diff.b, tot.diff.c contain the signals coming from the
transcriptome of the differentiated cell line.
tot.undiff.a, tot.undiff.b, tot.undiff.c contain the signals coming
from the transcriptome of the undifferentiated cell line.
pol.diff.a, pol.diff.b, pol.diff.c contain the signals coming from the
translatome of the differentiated cell line.
pol.undiff.a, pol.undiff.b, pol.undiff.c contain the signals coming
from the translatome of the undifferentiated cell line.
translatome.analysis is an object of class
TranslatomeDataset generated calling
newTranslatomeDataset() on expressionMatrix (see the
examples section for the exactcall).
limma.DEGs is an object of class DEGs generated
calling getDEGs() on expressionMatrix (see the examples
section for the exact call).
CCEnrichment is an object of class GOsets
generated calling GOEnrichment() on limma.DEGs (see the
examples section for the exact call).
CCComparison is an object of class GOsims
generated calling GOComparison() on CCEnrichment (see the
examples section for the exact call).
regulatory.elements.counts is an object of class data.frame
containing the background numbers of regulated and non-regulated genes
for each post-transcriptional regulatory factor considered by function
RegulatoryEnrichment.
regulatory.elements.regulated is an object of class data.frame containing the list of regulated genes for each post-transcriptional regulatory factor considered by function RegulatoryEnrichment
Source
Parent R, Kolippakkam D, Booth G, Beretta L. Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth. Cancer Res. 2007;67(9):4337-4345
##load the tRanslatome sample data
data(tRanslatomeSampleData)
Results
R version 3.3.1 (2016-06-21) -- "Bug in Your Hair"
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> library(tRanslatome)
Loading required package: limma
Loading required package: sigPathway
Loading required package: samr
Loading required package: impute
Loading required package: matrixStats
matrixStats v0.50.2 (2016-04-24) successfully loaded. See ?matrixStats for help.
Loading required package: anota
Loading required package: qvalue
Loading required package: DESeq
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following object is masked from 'package:limma':
plotMA
The following objects are masked from 'package:stats':
IQR, mad, xtabs
The following objects are masked from 'package:base':
Filter, Find, Map, Position, Reduce, anyDuplicated, append,
as.data.frame, cbind, colnames, do.call, duplicated, eval, evalq,
get, grep, grepl, intersect, is.unsorted, lapply, lengths, mapply,
match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank,
rbind, rownames, sapply, setdiff, sort, table, tapply, union,
unique, unsplit
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.
Attaching package: 'Biobase'
The following objects are masked from 'package:matrixStats':
anyMissing, rowMedians
Loading required package: locfit
locfit 1.5-9.1 2013-03-22
Loading required package: lattice
Welcome to 'DESeq'. For improved performance, usability and
functionality, please consider migrating to 'DESeq2'.
Loading required package: edgeR
Loading required package: RankProd
Loading required package: topGO
Loading required package: graph
Loading required package: GO.db
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: IRanges
Loading required package: S4Vectors
Attaching package: 'S4Vectors'
The following objects are masked from 'package:base':
colMeans, colSums, expand.grid, rowMeans, rowSums
Loading required package: SparseM
Attaching package: 'SparseM'
The following object is masked from 'package:base':
backsolve
groupGOTerms: GOBPTerm, GOMFTerm, GOCCTerm environments built.
Attaching package: 'topGO'
The following object is masked from 'package:IRanges':
members
Loading required package: org.Hs.eg.db
Loading required package: GOSemSim
Loading required package: Heatplus
Loading required package: gplots
Attaching package: 'gplots'
The following object is masked from 'package:IRanges':
space
The following object is masked from 'package:S4Vectors':
space
The following object is masked from 'package:stats':
lowess
Loading required package: plotrix
Attaching package: 'plotrix'
The following object is masked from 'package:gplots':
plotCI
> png(filename="/home/ddbj/snapshot/RGM3/R_BC/result/tRanslatome/tRanslatomeSampleData.Rd_%03d_medium.png", width=480, height=480)
> ### Name: tRanslatomeSampleData
> ### Title: Sample data set for tRanslatome
> ### Aliases: tRanslatomeSampleData translatome.analysis CCEnrichment
> ### limma.DEGs tRanslatomeData expressionMatrix CCComparison
> ### regulatory.elements.counts regulatory.elements.regulated
> ### Keywords: datasets
>
> ### ** Examples
>
> ##load the tRanslatome sample data
> data(tRanslatomeSampleData)
>
>
>
>
>
> dev.off()
null device
1
>