RareData
(Package: BVS) :
Simulated Example Rare Variant data set.
Simulated data set of 134 rare variants. The first column represents the disease status of the individual, the remaining columns the counts of minor alleles (0|1|2) for each variant.
PNAT study-based simulated data set of 122 variants as described in Quintana and Conti (submitted). The first column represents the disease status of the individual, the remaining columns the counts of minor alleles (0|1|2) for each variant. The simulation was created by using the genotype data from a systems-based candidate gene study of smoking cessation as part of the Pharmacogenetics of Nicotine Addiction and Treatment Consortium. In particular, data set was formed from genotypes of 122 variants within 789 individuals. The 122 variants are from 7 unique gene regions and thus are comprised of a great deal of correlation between the markers within each gene. In this simulation we assumed that the predictor-level covariate corresponding to the gene CHRNB2 was informative with regards to which variants are associated with smoking cessation.
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