Calculate rescaled variances, empirical variances, etc. For use with RUV model fits produced using RUVfit .
● Data Source:
BioConductor
● Keywords:
● Alias: RUVadj
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Provides an interface similar to lmFit from limma to the RUV2 , RUV4 , RUVinv and RUVrinv functions from the ruv package, which facilitates the removal of unwanted variation in a differential methylation analysis. A set of negative control variables, as described in the references, must be specified.
● Data Source:
BioConductor
● Keywords:
● Alias: RUVfit
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Subset-quantile Within Array Normalisation (SWAN) is a within array normalisation method for the Illumina Infinium HumanMethylation450 platform. It allows Infinium I and II type probes on a single array to be normalized together.
● Data Source:
BioConductor
● Keywords:
● Alias: SWAN, SWAN.MethyLumiSet, SWAN.RGChannelSet, SWAN.default
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Compute estimated coefficients, standard errors and LogVarRatios for a given set of contrasts.
● Data Source:
BioConductor
● Keywords:
● Alias: contrasts.varFit
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Plot the overall density distribution of beta values and the density distributions of the Infinium I and II probe types.
● Data Source:
BioConductor
● Keywords:
● Alias: densityByProbeType
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Extracts the intensity data for the 613 Illumina negative controls found on 450k arrays and returns a matrix of M-values (log2 ratio of the green to red intensities).
● Data Source:
BioConductor
● Keywords:
● Alias: getINCs
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Obtain absolute or squared Levene residuals for each CpG given a series of methylation arrays
● Data Source:
BioConductor
● Keywords:
● Alias: getLeveneResiduals
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Given a set of CpG probe names and optionally all the CpG sites tested, this function outputs a list containing the mapped Entrez Gene IDs as well as the numbers of probes per gene, and a vector indicating significance.
● Data Source:
BioConductor
● Keywords:
● Alias: getMappedEntrezIDs
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Tests gene ontology enrichment for significant CpGs from Illumina's Infinium HumanMethylation450 array, taking into account the differing number of probes per gene present on the array.
● Data Source:
BioConductor
● Keywords:
● Alias: gometh
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Given a user specified list of gene sets to test, gsameth tests whether significantly differentially methylated CpG sites are enriched in these gene sets.
● Data Source:
BioConductor
● Keywords:
● Alias: gsameth
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