Last data update: 2014.03.03
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GENESIS
Package: GENESIS
Type: Package
Title: GENetic EStimation and Inference in Structured samples
(GENESIS): Statistical methods for analyzing genetic data from
samples with population structure and/or relatedness
Version: 2.2.2
Date: 2016-4-1
Author: Matthew P. Conomos and Timothy Thornton
Maintainer: Matthew P. Conomos <mconomos@uw.edu>
Description: The GENESIS package provides methodology for estimating,
inferring, and accounting for population and pedigree structure
in genetic analyses. The current implementation provides
functions to perform PC-AiR (Conomos et al., 2015, Gen Epi) and PC-Relate
(Conomos et al., 2016, AJHG). PC-AiR performs a Principal Components
Analysis on genome-wide SNP data for the detection of population
structure in a sample that may contain known or cryptic relatedness.
Unlike standard PCA, PC-AiR accounts for relatedness in the sample
to provide accurate ancestry inference that is not confounded by
family structure. PC-Relate uses ancestry representative principal
components to adjust for population structure/ancestry and accurately
estimate measures of recent genetic relatedness such as kinship
coefficients, IBD sharing probabilities, and inbreeding coefficients.
Additionally, functions are provided to perform efficient variance
component estimation and mixed model association testing for both
quantitative and binary phenotypes.
License: GPL-3
Depends: GWASTools
Imports: Biobase, gdsfmt, graph
Suggests: SNPRelate, SeqArray, SeqVarTools, RUnit, BiocGenerics, knitr
VignetteBuilder: knitr
biocViews: SNP, GeneticVariability, Genetics, StatisticalMethod,
DimensionReduction, PrincipalComponent, GenomeWideAssociation,
QualityControl, BiocViews
NeedsCompilation: no
Packaged: 2016-05-16 05:18:52 UTC; biocbuild
● BiocViews: BiocViews, DimensionReduction, GeneticVariability, Genetics, GenomeWideAssociation, PrincipalComponent, QualityControl, SNP, StatisticalMethod
●
3 images,
12 functions,
1 datasets
●
Reverse Depends: 0
Install log
* installing to library '/home/ddbj/local/lib64/R/library'
* installing *source* package 'GENESIS' ...
** R
** data
** inst
** preparing package for lazy loading
** help
*** installing help indices
converting help for package 'GENESIS'
finding HTML links ... done
GENESIS-package html
HapMap_ASW_MXL_KINGmat html
assocTestMM html
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/assocTestMM.Rd:61: missing file link 'GenotypeData'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/assocTestMM.Rd:61: missing file link 'MatrixGenotypeReader'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/assocTestMM.Rd:61: missing file link 'GdsGenotypeReader'
fitNullMM html
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/fitNullMM.Rd:70: missing file link 'ScanAnnotationDataFrame'
king2mat html
pcair html
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcair.Rd:72: missing file link 'GenotypeData'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcair.Rd:72: missing file link 'MatrixGenotypeReader'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcair.Rd:72: missing file link 'GdsGenotypeReader'
pcairPartition html
pcrelate html
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcrelate.Rd:64: missing file link 'GenotypeData'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcrelate.Rd:64: missing file link 'MatrixGenotypeReader'
Rd warning: /tmp/RtmpZ2VzRi/R.INSTALL542a310b1336/GENESIS/man/pcrelate.Rd:64: missing file link 'GdsGenotypeReader'
pcrelateMakeGRM html
pcrelateReadInbreed html
pcrelateReadKinship html
plot.pcair html
varCompCI html
** building package indices
** installing vignettes
** testing if installed package can be loaded
* DONE (GENESIS)
Making 'packages.html' ... done
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